Master (M2) students interested in the study of #mRNA degradation mechanisms, their conservation and divergence - a new project on Cryptococcus neoformans molecular biology is underway at the Pasteur Institute in Paris (training period starting January 2024):

https://www.cosminribo.eu/posts/2023-03-m2topic/

#selfpromotion #yeastbiology #cryptococcus #RNAdegradation

Went on #wikipedia to see what information about #NMD can be found there. Many, many things are missing, while ridiculously detailed descriptions of pathology linked with NMD perturbation are present. Changing the page: a new goal for the winter holidays.

https://en.m.wikipedia.org/wiki/Nonsense-mediated_decay

#science #ribosome #RNAdegradation

#NMD is an RNA degradation pathway that should be taken into account whenever we look at transcripts reaching the cytoplasm of eukaryotic cells. Especially if those transcripts do not have an obvious coding part. Short, randomly present open reading frames are perfectly capable of troubling ribosomes and trigger #RNAdegradation through NMD (#lncRNAs, I'm looking at you).

#RNA biology

#NMD is an RNA degradation pathway that should be taken into account whenever we look at transcripts reaching the cytoplasm of eukaryotic cells. Especially if those transcripts do not have an obvious coding part. Short, randomly present open reading frames are perfectly capable of troubling ribosomes and trigger #RNAdegradation through NMD (#lncRNAs, I'm looking at you).