#IDMastodon #antiboticresistance @ScienceMagazine Genomic analysis of 51,229 #Mycobacteriumtuberculosis clinical isolates has identified an essential transcriptional regulator, Rv1830, herein called resR for resilience regulator, as a frequent target of positive (adaptive) selection. resR mutants do not show canonical drug resistance or drug tolerance but instead shorten the post-antibiotic effect
https://www.science.org/doi/epdf/10.1126/science.abq2787