🔸#CancerVaccine🔸
In a study published in Advanced Healthcare Materials, a team of MIT researchers engineered a therapeutic cancer vaccine capable of restoring STING signaling and eliminating the majority of tumors in mouse models of colon cancer and melanoma, with minimal side effects. The vaccine also inhibited metastasis in a breast cancer mouse model and prevented the recurrence of tumors in cured mice.

"Moderna/Merck cancer vaccine plus Keytruda delays skin cancer return

An experimental mRNA cancer vaccine developed by Moderna Inc (MRNA.O) and Merck & Co (MRK.N) cut the risk of death or recurrence of the most deadly skin cancer by 44% compared with Merck's immunotherapy Keytruda alone, U.S. researchers reported"

🔗: https://www.reuters.com/business/healthcare-pharmaceuticals/moderna-cancer-vaccine-with-mercks-keytruda-delays-return-deadly-skin-cancer-2023-04-16/

#cancer #SkinCancer #vaccine #CancerVaccine #science

Cancer and heart disease vaccines ‘ready by end of the decade’

https://www.theguardian.com/society/2023/apr/07/cancer-and-heart-disease-vaccines-ready-by-end-of-the-decade?CMP=Share_iOSApp_Other “An #mRNA-based #CancerVaccine would alert the #ImmuneSystem to a cancer that is already growing in a patient’s body, so it can attack and destroy it, without destroying healthy cells.

This involves identifying #protein fragments on the surface of cancer cells that are not present on healthy cells”

Moderna and Merck report #cancervaccine progress data. What does this mean for #pediatriccancers? #StJude immunologist Dr. Paul Thomas: “We know pediatric tumors elicit immune responses, but we aren't as good at enlisting those responses to destroy the tumor as we are in some adult cancers. We should turn to understanding what vaccine features, and the elicited responses, drive the observed efficacy and determine whether we can create these responses in lower mutation-burden pediatric tumors.”

Researchers say they have successfully completed a trial of a personalised #CancerVaccine that uses the same messenger-RNA technology as Covid jabs. The experimental vaccine, made by Moderna and Merck, is designed to prime the immune system to seek and destroy cancerous cells. #oncology #nursing #MedMastodon #healthcare

https://www.bbc.co.uk/news/health-63959843

#SyntheticBiology #tumors #CART #TRUCKs #ICTs #iPSCs #macrophages #TCells #NKCells #bioengineering #CancerVaccine

மார்பக புற்றுநோய் பரிசோதனை தடுப்பூசி மனிதர்களுக்கான முதல் கட்ட சோதனை வெற்றி https://patrikai.com/experimental-breast-cancer-vaccine-succeeds-in-first-phase-of-human-trial/ via @patrikaidotcom@twitter.com

#oncology #breastcancer #CancerResearch #CancerVaccine #vaccine #CANCER