This is neat!
A paper in @eLife from Anne-Catherine Prats lab (U Toulouse) looking at #IRES regulation.
They show that #mRNA with IRES in #cardiomyocytes interactes with #lncRNA NEAT1 in nuclear paraspeckles, and suggest an assembly of an "IRESome" -with paraspeckle-related proteins - that regulates IRES-dependent translation (here - upon hypoxia).
#lncRNA #cardiomyocytes #mRNA #ires
A novel study we contributed to provides the first detailed analysis of 3D #chromatin organisation changes during the development of #endothelium, and how they correlate with gene expression regulations. The study also compares these dynamics with those we previously reported for #cardiomyocytes. Kudos Kris and Katie for spearheading this work! #UW #ISCRM #4DNucleome
https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(22)00536-7
#4dnucleome #iscrm #UW #cardiomyocytes #endothelium #chromatin
RT @endothelialnews@twitter.com
😮 A must-read article about cell-cell contact ☎️ in @ScienceMagazine@twitter.com!
Researchers find that #endothelial cells in the developing heart were genetically labeled after contact with neighboring #cardiomyocytes.
✨ More interesting results here: https://bit.ly/3h2qm5U
🐦🔗: https://twitter.com/endothelialnews/status/1598789626256191489