'Germline hemizygous loss-of-function mutations affecting the actin regulator DOCK11 were shown to cause a previously unknown inborn error of hematopoiesis and immunity characterized by severe immune dysregulation and systemic inflammation, recurrent infections, and anemia.'
#Immunology #humanimmunology
https://www.nejm.org/doi/full/10.1056/NEJMoa2210054?query=featured_home
RT @BrodinPetter@twitter.com
Very interesting and detailed analyses of Monocytes during mild/moderate acute #COVID19 showing functional and metabolic adaptation and pro-thrombotic states of relevance to #LongCovid - Terrific #HumanImmunology by @MDV_Lab@twitter.com @imperialcollege@twitter.com https://www.nature.com/articles/s41467-022-35638-y
š¦š: https://twitter.com/BrodinPetter/status/1610366922771824646
#COVID19 #LongCovid #humanimmunology
First steps here and learning! Time for #introduction part2 with hashtags. Iām a physician-scientist in Helsinki š«š® (the happiest people on Earth live here!) and topics close to my heart are (not in any order) #thymus #myastheniagravis #aps1 #AIRE #helios #Tfh #tregs #MAITs #RTEs #thymopoiesis #immunodeficiency #immunology #immunophenotyping #flowcytometry #humanimmunology #viruses #viralimmunology #GerminalCenters #SingleCell #Transcriptomics - here to read and learn more about these!
#Transcriptomics #SingleCell #GerminalCenters #viralimmunology #viruses #humanimmunology #flowcytometry #immunophenotyping #immunology #immunodeficiency #thymopoiesis #rtes #maits #tregs #Tfh #helios #aire #aps1 #myastheniagravis #thymus #introduction