#IDMastodon #Immunology Oview & Understanding of sex differences in #immunometabolism #viralinfections ( #SarsCoV2 ) prophylaxis and therapy
https://www.frontiersin.org/articles/10.3389/fimmu.2023.1259382/full?utm_source=S-TWT&utm_medium=SNET&utm_campaign=ECO_FIMMU_XXXXXXXX_auto-dlvrit

Postdoc in Immunometabolism

University of Central Florida

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-central-florida-27778-postdoc-in-immunometabolism/?feed_id=49867

#ScienceJobs #hiring #research #Immunometabolism, #Cancer Immunotherapy, #GVHD, #Systemic Immunology
ORLANDO #UnitedStatesUS #PostdoctoralFellow
https://jobrxiv.org/job/university-of-central-florida-27778-postdoc-in-immunometabolism/?feed_id=49867

RT @RyanLab_MBU
🚨Last weeks #immunometabolism discoveries🚨 @Bims_BiomedNews ⬇️⬇️⬇️

http://biomed.news/bims-imicid/2023-04-23

Highlights:

I) MYC-SLC7A5-glycolysis metabolic axis regulates MAIT cell proliferation & is impaired in obesity
II) Hypusination regulates SREBP2 translation & enterovirus infection

>100 RNA binding proteins identified that bind to 3’UTR of cytokine mRNA (IFNg, TNF and IL2) in Human T cells.

#immunometabolism finding (Supl Tables 1 and 3)
GAPDH binding to cytokine 3’UTR in PMA/Ionomycin activated, but not untreated, Human T cells.

https://doi.org/10.1016/j.celrep.2023.112419

What would I do without @RyanLab_MBU ‘s weekly roundup of the new #immunometabolism papers? Thank you Dylan for making it so easy to keep up to date. You’re an absolute ⭐️.

RT @RafaJArguello
📢🙏 share and help us to find a motivated PhD candidate for an 🤯🤓🤩 opportunity at @CancerImmunoAMU

🧪🧠 Exciting #PhD call in #PediatricOncology! to advance #Medulloblastoma research using innovative single-cell metabolomic profiling! @SCENITHmetab #ImmunoMetabolism

1/

Also in @sciencemagazine this week: Giuseppe Matarese pens a Perspective on the link between #obesity and #autoimmunity!

https://bit.ly/Sci_ade0113

#immunometabolism #overnutrition #T1D #MS #Tregs #adipocytes #CaloricRestriction #immunotherapy

M1 macrophage - fragmented mitochondria - glycolytic

M2 macrophage - elongated mitochondria - FAO

Also opposite to correlation described by Ngo et al. in non immune cells:
https://doi.org/10.15252/embj.2022111901

🤨 something different it’s going on in #Immunometabolism

Any other examples?

Amazing opportunity for anyone looking for a postdoc. #immunometabolism, #mitochondria and the chance to work with the immensely talented Dylan Ryan
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RT @RyanLab_MBU
🚨To #immunometabolism and #mitochondria lovers everywhere🚨

There is an opportunity to join the newly minted Ryan group @MRC_MBU @Cambridge_Uni as a postdoctoral research associate.

Please check out the advert below and I appreciate any shares⬇️⬇️⬇️

https://www.nature…
https://twitter.com/RyanLab_MBU/status/1636713209913569281

RT @metab_innate
Are you an #immunometabolism enthusiast? I'm excited to share our latest work out now in @Nature. This work was jointly led by @AlexHooftman, @ChristianGPeace & I, examining mitochondrial TCA cycle function in inflammatory macrophages 1/n
https://www.nature.com/articles/s41586-023-05720-6

RT @ReboldiLab
Check out our #immunometabolism study on how Tgd17 cells are educated in the thymus to sense oxysterol through GPR183 and home to the skin towards depots of GPR183 ligand. A fantastic collaboration between our lab and Joonsoo Kang’s lab. #gammadeltaTcells #keratinocytes https://twitter.com/frascolimichela/status/1629518406759202817

RT @VZBittencourt
Impact of butyrate on NK cells function and metabolism is finally out! Data from my postdoc 😍 🌈🥳 thanks @Elizabe28913853 for all the support ❤️

#nkcells #butyrate #immunometabolism #guthealth https://www.nature.com/articles/s41598-023-29731-5

RT @LaguetteNadine
#JobAlert ! We are looking for 3 #postdoctoral fellows and 1 #bioinformatician, with expertise in #innateimmunity, #immunometabolism, #adipocyte biology, and/or #singlecell technologies. Contact me, if you would be interested to join us, in sunny Montpellier !

Location, location, location!!

Great study by @cris_f_aguiar and @MoraeaPedro showing that the tissue of resistance dictates iNKT cell metabolism, and lots more…..

A must read for all #Immunometabalikes out there.
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RT @cris_f_aguiar
@CellReports had a great timing on putting the paper online the day after my birthday 🎁 Thanks!
We are happy to share our work on iNKT cell metabolism 👇🏼 #nktcells #immunometabolism
https://www.cell…
https://twitter.com/cris_f_aguiar/status/1617569764271964161

What do your MAITs like to eat?

‘MAITabolism2 – the emerging understanding of MAIT cell metabolism and their role in metabolic disease’ - great review from @KediaMehta and @AndyHogan82
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RT @KediaMehta
The full version of our new review is out now, discussing MAIT cell metabolism and MAIT cells in metabolic diseases. @AndyHogan82 #immunometabolism #MAITcell https://www.frontiersin.org/articles/10.3389/fimmu.2022.1108071/full?utm_sou…
https://twitter.com/KediaMehta/status/1615982362474565632

RT @metab_innate
🚨Last weeks #immunometabolism findings🚨@Bims_BiomedNews ⬇️⬇️⬇️

http://biomed.news/bims-imicid/2023-01-15

My highlights:
I) @DoctorKvoss & @JeffRathmell find T cell impairment in SLE arises from elevated Transferrin receptor & iron uptake @SciImmunology
II) GOT1 & CD8+ T cells @CellReports

RT @metab_innate
🚨Last weeks #immunometabolism discoveries @Bims_BiomedNews ⬇️⬇️⬇️

http://biomed.news/bims-imicid/2023-01-08

My highlights:

I) Microbial metabolite harmaline protects systemic inflammation via bile acid-GPR5 signalling
II) Sphingosine synthesis and S1P promote mito fission and trained immunity

RT @metab_innate@twitter.com

Happy New Year All🎉Last weeks #immunometabolism discoveries @Bims_BiomedNews@twitter.com @ImmunoMet@twitter.com ⬇️⬇️⬇️

http://biomed.news/bims-imicid/2023-01-01

My highlights:

I) SREBP-driven metabolic remodelling is required for B cell function
II) PPP supports mac efferocytosis
III) Amino acid regulation of ILC2s

🐦🔗: https://twitter.com/metab_innate/status/1609562570075119619

RT @DavidFinlayTCD@twitter.com

Engineering amino acid metabolism in CAR-T cells #Slc7a5 #Slc7a11

Very interesting approach. We are now regularly seeing metabolic engineering strategies to improve cellular immunotherapies.
#immunometabolism

https://ashpublications.org/bloodadvances/article/doi/10.1182/bloodadvances.2022008272/493733/Engineering-amino-acid-uptake-or-catabolism

🐦🔗: https://twitter.com/DavidFinlayTCD/status/1604539810558918658

Engineering amino acid metabolism in CAR-T cells #Slc7a5 #Slc7a11

Very interesting approach. We are now regularly seeing metabolic engineering strategies to improve cellular immunotherapies.
#immunometabolism

https://ashpublications.org/bloodadvances/article/doi/10.1182/bloodadvances.2022008272/493733/Engineering-amino-acid-uptake-or-catabolism