Detection of primary myelofibrosis in blood serum via Raman spectroscopy assisted by machine learning approaches; correlation with clinical diagnosis.
Nanomedicine: Nanotechnology, Biology and Medicine
Available online 25 August 2023, 102706
https://doi.org/10.1016/j.nano.2023.102706
#ramaneffect #myelofibrosis

Application of Fourier Transform InfraRed spectroscopy of machine learning with Support Vector Machine and principal components analysis to detect biochemical changes in dried serum of patients with primary myelofibrosis.
Biochimica et Biophysica Acta (BBA) - General Subjects
(2023) 130438
https://doi.org/10.1016/j.bbagen.2023.130438
#infrared #ml #myelofibrosis

@Nature Biological drivers of clinical phenotype in #myelofibrosis https://www.nature.com/articles/s41375-022-01767-y

#oncologyresearch Impact of TP53 on outcome of patients with #myelofibrosis undergoing hematopoietic stem cell transplantation @BloodJournal . TP53MT patients harbored more frequently complex karyotype & unfavorable cytogenetic risk, were less likely to receive pre-transplant ruxolitinib, & underwent more frequently high-intensity conditioning regimens vs TP53WT group.
https://ashpublications.org/blood/article/doi/10.1182/blood.2023019630/495000/Impact-of-TP53-on-outcome-of-patients-with

RT @RareRevolutionM@twitter.com

Jeff is the primary caregiver for his wife, Summer, who was diagnosed with #myelofibrosis in 2017. He reflects on the importance of building a care team and how #patients and #caregivers can work together. https://rarerevolutionmagazine.com/digitalspotlight/living-with-myelofibrosis-a-caregivers-perspective-on-the-importance-of-teamwork-and-a-positive-mindset

🐦🔗: https://twitter.com/RareRevolutionM/status/1601200424157167622

RT @RareRevolutionM@twitter.com

Special thanks to our contributors for providing their impactful perspectives on #myelofibrosis and to @GSK@twitter.com for sponsoring this inspiring series. To access this #DigitalSpotlight, visit our site: https://rarerevolutionmagazine.com/digital_spotlights/myelofibrosis

🐦🔗: https://twitter.com/RareRevolutionM/status/1596881807705776132

RT @RareRevolutionM@twitter.com

Carly was diagnosed with #myelofibrosis at age 25. Read how her challenges gave her insight into issues younger MF patients face.https://rarerevolutionmagazine.com/digitalspotlight/myelofibrosis-in-young-people-carly-pierces-treatment-with-a-stem-cell-transplant-at-33-years-old/

🐦🔗: https://twitter.com/RareRevolutionM/status/1595371829237096448

What if we could recapitulate the complexity of human #bonemarrow in an #organoid model?

Enjoy this excellent research article by Abdullah Khan and colleagues at University of Birmingham and University of Oxford:

Human bone marrow organoids for #disease #modelling, discovery and validation of therapeutic #targets in hematological malignancies

Article in Cancer Discovery: https://aacrjournals.org/cancerdiscovery/article/doi/10.1158/2159-8290.CD-22-0199/710534/Human-bone-marrow-organoids-for-disease-modelling

#hematopoiesis #myelofibrosis #leukemia