Incredible

RT @MoniqueWasunna@twitter.com

We are happy to announce that we now have a simpler treatment for #sleepingsickness with 95% efficacy. The study results were published in @TheLancetInfDis@twitter.com

The single-dose of acoziborole💊 is being developed by @DNDi@twitter.com and @sanofi@twitter.com. #beatNTDs

Read more➡️ http://bit.ly/3EP4oeD

🐦🔗: https://twitter.com/MoniqueWasunna/status/1597970870458232833

Exciting results on a new sleeping sickness drug: 95% effective in late stage patients, and 100% effective in those diagnosed early in a trial in the DRC & Guinea. Could this be the beginning of the end of the disease?

https://www.telegraph.co.uk/global-health/science-and-disease/new-cure-sleeping-sickness-could-eliminate-nightmare-disease/

Also more stunning 🦟 pics from Simon Townsley..

#neglecteddiseases #sleepingsickness #globalhealth #tsetseflies

New research article in The Lancet Infectious Diseases> Efficacy and safety of #acoziborole in patients with human African #trypanosomiasis caused by #Trypanosoma brucei gambiense: a multicentre, open-label, single-arm, phase 2/3 trial https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00660-0/fulltext #gambienseHAT #SleepingSickness

#Parasitology paperwatch: justifiably bullish update on progress towards elimination of #HAT (#SleepingSickness) as a public health concern, & an outstanding example of the health benefits that can be achieved when national and international organisations can work together in a coordinated and sustained way to achieve a set goal.

Enriched by some useful charts of incidence and geographical distribution that are due to feature heavily in introductory slides for scientific talks over the next few years.

Despite the good news, the article maintains a sober and appropriately cautious tone throughout, noting caveats and remaining challenges while still previewing the next big target: elimination of #gHAT transmission

https://dx.plos.org/10.1371/journal.pntd.0010047

"Few clinical trials account for timing of treatment, but there are signs that doing so could have broad benefits"

Sporting night vision goggles, a scientist probes the internal clocks that help parasites infect people https://www.statnews.com/2022/11/21/parasites-circadian-rhythm-infection-rijo-ferreira/ #SleepingSickness #malaria