#ALS clock is ticking. Join us w/ @TomislavSokol for the #EUALSCoalition policy paper launch and high-level panel on 7 Sept @europarl_en to discuss how to ensure better care & treatment for people living w/ this rare neurodegenerative disease. Sign up:https://vu.fr/PnJJ

🐦🔗: https://n.respublicae.eu/istvan_ujhelyi/status/1681996417877831680

From Nov. '22; still relevant. Interesting questions/thoughts — "Twitter, #Mastodon and the #Fediverse: I Have Questions" https://sogrady.org/2022/11/13/twitter-mastodon-and-the-fediverse-i-have-questions/

I saw it posted by @rabbinathan whose post discusses funding/economic issues (https://babka.social/@rabbinathan/110543026636375994). Blog author @sogrady discusses more. [NB: Search challenges on Mastodon often bug me, but it was pretty easy to find O'Grady in the fediverse. He's got a fun blog, too, & mentions the #ALS Association — #MND #ELA #SLA — so 👍 https://www.als.org/]

Referenced link: https://medicalxpress.com/news/2023-06-remnants-ancient-virus-fuel-als.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-06-remnants-ancient-virus-fuel-als.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1666159430075809826#m

RT by @physorg_com: Remnants of ancient virus may fuel #ALS, says new research @elife https://elifesciences.org/articles/79452 https://medicalxpress.com/news/2023-06-remnants-ancient-virus-fuel-als.html

🔊Voting für #Deutscherpodcastpreis läuft! Wir freuen uns über Stimmen ➡️ https://deutscher-podcastpreis.de/podcasts/hirn-heinrich-der-wissenspodcast-des-dzne/ 👉 #SabineHeinrich
🧠 #Demenz #Alzheimer #Parkinson #ALS #FTD 🎙️ #podcast #podcastpreis #dpp2023 #dpp23 /mn

US Senate kicks off fresh round of drug pricing control legislation —FDA approves Biogen and Ionis’ Tofersen for rare genetic form of ALS—Novartis culls 10% of pipeline, doubles down on five core therapeutic areas-- See more on our front page news http://bit.ly/w28kSd #earnings #biogen #novartis #senate #legislation #drugpricing #als #pharma #pharmanews #biotech #biopharma #biotechnology #cafepharma

RT @UniCologne
🧊Kälte fördert gesundes #Altern. Forschende des @TheVilchezLab @CECAD_ haben jetzt in Caenorhabditis elegans herausgefunden, wie Kälte den Abbau von Eiweißansammlungen, die bei Alternserkrankungen wie #ALS oder #Huntigton auftreten, fördert.
Mehr dazu ➡https://uni.koeln/CE9LW

Check out the latest paper from my buddy @TheVilchezLab on aging. The third paper today from my smart friends! V r doing well.
---
RT @TheVilchezLab
New work from the lab @NatureAging!❄️Lowering body temperature extends #longevity. We find that cold-induced #proteostasis prevents #aging and aggregation of proteins that cause age-related diseases #ALS #HuntingtonDisease in C. elegans and human cells https://www.nature.com/articles/s43…
https://twitter.com/TheVilchezLab/status/1642908783327207426

Novartis' Kisqali cuts recurrence risk in early-stage breast cancer — BioNTech's COVID-19 vaccine revenue forecasts lower than expected— BrainStorm secures FDA adcomm for ALS therapy NurOwn -- See more on our front page news http://bit.ly/w28kSd #novartis #breastcancer #biontech #vaccines #earnings #als #fda #pharma #pharmanews #biotech #biopharma #biotechnology #cafepharma

So much in this article:

“Unless the president of the United States would declare #Alzheimer's a national emergency … that, I’ve been told, is the only way this could be done.” — Alberto Ascherio

"Scientist who uncovered likely leading cause of MS (i.e., Epstein-Barr infection) wants to tackle #ALS next" https://www.statnews.com/2023/03/16/alberto-ascherio-multiple-sclerosis-als/

#MND #ELA #SLA #EBV

It's Mom's birthday today, in addition to the 3rd anniversary of pandemic lockdowns around here. Mom died seven years ago. Also my in-laws' 60th anniversary. Mom died the day after my folks' 60th anniversary, of #ALS #MND #ELA #SLA (same miserable disease, different languages). Dad was holding her hand. Don't tell me willpower isn't a real force.

Had a small celebration with my in-laws last night.

Life *is* complicated. Feeling it all, right now.

RT @dalecandela: #8M La ELA tiene nombre de mujer.
Hoy y todos los días, nuestro apoyo y reconocimiento a todas las mujeres que, directa o indirectamente, luchan contra esta enfermedad.

#dalecandELA
#juntoscontralaELA
#ELA #ALS
#DíaInternacionaldelaMujer

🐦🔗: https://n.respublicae.eu/IzaskunBilbaoB/status/1633452416422010880

Wir freuen uns schon morgen am #TagderseltenenErkrankungen, dazu gehören u. a. #Ataxie oder #ALS, aber eben auch #Huntington, zu einem Instragram-Live-Talk einzuladen. Ab 16 Uhr starten wir drüben 👉https://www.instagram.com/dzne_de /db

Referenced link: https://medicalxpress.com/news/2023-02-calming-destructive-cells-als-independent.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-02-calming-destructive-cells-als-independent.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1629049958845276165#m

RT by @physorg_com: Calming the destructive cells of #ALS by two independent approaches @northwesternu https://www.nature.com/articles/s41434-023-00383-4 https://medicalxpress.com/news/2023-02-calming-destructive-cells-als-independent.html

Brent Saunders to return as Bausch + Lomb CEO — Amylyx counters Wall Street noise, cites demand for ALS drug—New VC Curie.bio makes its debut with $500m+ war chest-- See more on our front page news http://bit.ly/w28kSd #bauschandlomb #ceo #brentsaunders #als #funding #venturecapital #biotech #biotechnology #biopharmaceuticals #pharma #pharmanews #cafepharma

@beaveinflow True words. Thanks for sharing. #ALS #MND #ELA #SLA — different initials, different countries, same awful disease — is terrible. Let's hope for progress on treatments soon.

Features That May Make Motor Neurons Vulnerable to ALS

Motor neurons are distinguished by a set of genes that may enable the large size of the motor neuron cell body and lengthy axon, but also underlie their vulnerability to degeneration. Their molecular profile was defined by genes involved in cytoskeletal structure, which gives the cell shape and organizes the structures within; neurofilament genes related to cell size; and genes linked to the onset of ALS.

#Neuroscience #SpinalCord #Neuron #Motorneuron #MotorneuronDisease #ALS #NeurodegenerativeDiseases #NeurologicalDiseases #Transcriptomics

https://neurosciencenews.com/als-motor-neurons-genetics-22436/

A cellular taxonomy of the adult human spinal cord
Single-nucleus RNA sequencing and spatial transcriptomics of adult human spinal cord

#Neuroscience #SpinalCord #Neuron #Motoneuron #MotoneuronDisease #ALS #NeurodegenerativeDiseases #NeurologicalDiseases #Transcriptomics

https://www.cell.com/neuron/fulltext/S0896-6273(23)00031-4?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0896627323000314%3Fshowall%3Dtrue

@sdkstl Thanks for putting this here. Raw, honest writing.

I used to post about #ALS #MND #ELA #SLA (same awful disease as abbreviated in several different languages) on the other site. Have not found quite the same community here — yet. It will happen.

Pfizer’s full-year revenues grow 23%, top $100B — UniQure nabs another gene therapy for ALS — AstraZeneca, Novo Nordisk and Sanofi score 340B-related appeals court win over HHS -- See more on our front page news http://bit.ly/w28kSd #pfizer #earnings #als #340B #hhs #astrazeneca #novonordisk #sanofi #drugdiscounts #pharma #pharmanews #biotech #biopharma #biotechnology #cafepharma

Congrats to Wan Seok Yang and his team on their paper analyzing #ferroptosis in motor neurons! Here are my thoughts and a link to his paper. #science #ALS @columbia_bio https://brentstockwell.medium.com/mouse-motor-neurons-derived-from-embryonic-stem-cells-undergo-ferroptosis-a-link-to-als-82969cebc490