Sarah Melamed · @Curiousphage
113 followers · 52 posts · Server fediscience.orgThe antitumour effects of caloric restriction are mediated by the gut microbiome
https://www.nature.com/articles/s42255-022-00716-4
#cancer #microbiome #diet #Antitumor
#Antitumor #diet #microbiome #cancer
Alexis Verger · @AVerger
815 followers · 83 posts · Server fediscience.org
Amazing work showing that #genetic #disruption of the #kinase module (CDK) of Mediator complex in chimeric #antigen receptor T cell (CAR T) resulted in enhanced effector function and increased #antitumor activity (disruption of CDK module increases core Mediator #chromatin occupancy at #enhancers)
#enhancers #chromatin #Antitumor #antigen #Kinase #disruption #genetic #paperoftheday
Prathyusha Konda · @prats
137 followers · 87 posts · Server fediscience.org
RT @ScienceTM@twitter.com
Knocking out the transcription factors #BLIMP1 and #NR4A3 in #CART cells leads to higher #Antitumor activity in mice, shows new research from scientists at @PennMed@twitter.com.
Learn more: https://scim.ag/wp
🐦🔗: https://twitter.com/ScienceTM/status/1591521229755727873
#Antitumor #cart #NR4A3 #BLIMP1