A small RNA system ensures accurate homologous pairing & unpaired silencing of #meiotic #chromosomes in C. #elegans

Hiroaki Tabara et al show #argonaute proteins CSR-1 and CSR-2 targeting repeat-derived #lncRNAs to mediate both #synaptonemal complex formation and condensation of unpaired chromosomes

https://www.embopress.org/doi/10.15252/embj.2020105002

Long-B prokaryotic #Argonaute systems employ various effectors to confer immunity via abortive infection | bioRxiv

https://www.biorxiv.org/content/10.1101/2023.03.09.531850v1

RT @RoliRoberts
Nasty gut #nematode Heligmosomoides bakeri secretes siRNAs + a special #Argonaute protein (exWAGO) in #exosomes - these are enriched for transposon sequences & suppress host pathogen response - @amyhbuck (remote) "at" #EESSymbiosis [good remote speaker AV from @EMBLEvents, BTW]

mandatory factoid for all you #Argonaute fans! cool work reveals the Argonauta egg case is *not* evolutionarily related to the Nautilus shell, and not to other "true shells" in general...it's a novel convergent innovation! via @NYTimes@twitter.com https://www.nytimes.com/2022/11/05/science/octopus-shell-argonaut.html?smid=nytcore-ios-share&referringSource=articleShare