For the #astrocyte crowd?

Exclusive early bird price just for you -Recycling 2023
Dear Colleague‍ ,

I would like to take the privilege to invite you to be an honorable speaker and deliver a presentation at 2nd International Conference and Expo on Recycling and Waste Management during 26-27 June, 2023 at Paris, France. If possible, I would appreciate receiving your abstract submission on or before May. 20. 2023.

#AcademicSpam

For the #astrocyte lovers out there: fantastic new work from Aina Badia et al., showing ezrin-mediated PAP retraction in fear learning!
Such.Pretty.Data ❤️😍🌟

Retraction of Astrocyte Leaflets From the Synapse Enhances Fear Memory - Biological Psychiatry
https://www.biologicalpsychiatryjournal.com/article/S0006-3223(22)01705-X/fulltext#.Y9o3jEhUpdQ.twitter

Another not-to-be-missed talk from the WWN series, tomorrow @ 5pm CET

Cagla Eroglu | How do Astrocytes Sculpt Synaptic Circuits?
https://www.world-wide.org/seminar/8674/

#neuroscience #synapse #Astrocyte #systemsneuro #circuits

At the #PrecapillarySphincter and #NeurovascularUnit, I show: #EndothelialCell, #MuralCell, #Fibroblast, #Macrophage, #Astrocyte and #Neuron. Also, structures: #ContractileElement, #MyoendothelialJunction, #PinocyticVesicle, #Collagen, #Elastin, #Glycocalyx (6/15)

At the #PrecapillarySphincter and #NeurovascularUnit, I show: #EndothelialCell, #MuralCell, #Fibroblast, #Macrophage, #Astrocyte and #Neuron. Also, structures: #ContractileElement, #MyoendothelialJunction, #PinocyticVesicle, #Collagen, #Elastin, #Glycocalyx (6/15)

An integrated theory for #astrocyte function in #brain circuits and behavior
https://arxiv.org/abs/2211.09906

~50% Olig2+ #Astrocyte Progenitors migrate along blood vessel in prenatal🧠cortex🤠

Vessel-guided migration favors superficial cortex as Astrocyte destination

#EndothelialCell CXCL12-> AP CXCR4/7

Dr. Hidenori Tabata & Kazunori Nakajima labs Nat Comm 2022
https://www.nature.com/articles/s41467-022-34184-x

**Glial Cells**
The human brain contains 86B neurons and 85B Glia.

**Different types of Glia:**

🔸 Astrocytes: Astrocytes are really important type of Glia. They're essentially responsible for keeping the environment clean, they're the sanitation worker of the brain. So they are picking up all the refuse that the neurons have let loose including excess ions, excess #neurotransmitters and their metabolites.

They also are very important during development. They allow neurons to get to where they have to go during development. #Neurons are born in one place and they have to go some place else, and what highway did they take? They hitch on a progenitor cell that is going to become an #Astrocyte.

And, in addition when synapses are formed, the synapses are not maintained without some effort, and part of that is that the synapses are enveloped in the processes of #Astrocytes. So, there's a lot of structural and metabolic support that the Astrocytes are providing for neurons.

🔸 Oligodendrocytes and Schwann Cells: The #oligodendrocytes make myelin in the CNS and the #SchwannCells make it in the Peripheral Nervous System. So all these demyelinating diseases will affect either central myelin or peripheral #myelin. They will not affect both -- central or peripheral.

Because they are made by two different types. The Oligodendrocytes in the central nervous system and a Schwann cells in the peripheral nervous system.

🔸 Microglia: #Microglia are the one exception to the rule that
nervous system, that the cells of the nervous system come from Ectoderm. These are actually essentially immune cells coming from the blood lineage. These are immune cells that have invaded into the central nervous system and their job is to be quiet. And if we're healthy and everything goes well, they are quiet. But when there is a problem these microglia react, they try to rectify things, they try and bring some attention to areas of damage and what is emerging is that sometimes they go overboard and they start to participate in making the problem as well as solving the problem.