New research article in The Lancet Infectious Diseases> Efficacy and safety of #azithromycin versus placebo to treat lower respiratory tract infections associated with low #procalcitonin: a randomised, placebo-controlled, double-blind, non-inferiority trial https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00735-6/fulltext #LRTI

S pneumoniae in US commonly R to macrolides. Import to know if you are using it alone for RTI.

#Azithromycin #Stewardmeme #macrolides

https://academic.oup.com/ofid/article/8/7/ofab063/6128791

🔬 “Effect of #hydroxychloroquine with or without #azithromycin on the mortality of #COVID-19 patients: a systematic review and meta-analysis” (T. #Fiolet, A. #Guihur, M. #Rebeaud, M. #Mulot, N. #Peiffer-Smadja, Y. #Mahamat-Saleh, Clinical Microbiology and Infection 26/8/2020)
https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(20)30505-X/fulltext
“Hydroxychloroquine alone was not associated with reduced mortality in hospitalized COVID-19 patients but the combination of hydroxychloroquine and azithromycin significantly increased mortality.”3/3

RT @SumiSukanya@twitter.com

Dr Utpal Barman, an anaesthetist with Pratiksha hosptail in Ghaziabad died of massive cardiac arrest today. He had taken #Hydroxychloroquine (recommended by Indian govt for #COVID2019 prophylaxis) and #Azithromycin fr 2 days. This is extremely serious, please take note @ICMRDELHI@twitter.com

🐦🔗: https://twitter.com/SumiSukanya/status/1244321362610536448