“Hybrid immunity against #XBB was lower than against #BA4 or #BA5, especially in adolescents. Early #vaccination of previously uninfected children before their first #SARSCoV2 exposure could potentially strengthen population immunity resilience against future variants.”
#xbb #BA4 #BA5 #vaccination #SarsCoV2
BNT162b2 vaccine protection against omicron and effect of previous infection variant and vaccination sequence among children and adolescents in Singapore: a population-based cohort study - The Lancet Child & Adolescent Health https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(23)00101-3/fulltext “In previously infected children and adolescents, #BNT162b2 #vaccination provided additional protection against omicron #BA4 or #BA5 and #XBB #variants compared with those who remained #unvaccinated.
#BNT162b2 #vaccination #BA4 #BA5 #xbb #variants #unvaccinated
In den #USA empfiehlt die #CDC nun auch einen zweiten #BA4/5-Booster für Risikogruppen. In #Deutschland lässt man es lieber drauf ankommen nach dem Motto: „Es ist vorbei!“
#impfenschutzt #covid #CovidIsNotOver
https://www.cdc.gov/media/releases/2023/s0419-covid-vaccines.html
#usa #cdc #BA4 #deutschland #impfenschutzt #covid #CovidIsNotOver
#mRNA #vaccines and hybrid #immunity use different B cell #germlines against #Omicron #BA4 and #BA5 https://www.nature.com/articles/s41467-023-37422-y
#mrna #vaccines #immunity #germlines #omicron #BA4 #BA5
Protective immunity of #SARSCoV2 #infection & vaccines against medically attended symptomatic #omicron #BA4, #BA5, and #XBB reinfections in Singapore: a national cohort study
"Protection against XBB reinfection conferred by a previous omicron infection with vaccination was lower and waned faster than protection against BA.4 or BA.5 reinfection, which is indicative of the greater immune evasiveness of the XBB sublineage"
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00060-9/fulltext
#sarscov2 #infection #omicron #BA4 #BA5 #xbb #SARS2 #variants #covid19
Association of #SARS-CoV-2 #BA4/BA.5 #Omicron lineages with immune escape and #clinical outcome https://www.nature.com/articles/s41467-023-37051-5
[Articles] Protective #immunity of #SARS-CoV-2 #infection and #vaccines against medically attended symptomatic #omicron #BA4, #BA5, and #XBB #reinfections in #Singapore: a national cohort study https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00060-9/fulltext?rss=yes
#immunity #sars #infection #vaccines #omicron #BA4 #BA5 #xbb #Reinfections #singapore
#Immunity of heterologous and homologous boosted or #convalescent individuals against #Omicron #BA1, #BA2 and #BA4/5 variants https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiad057/7069351?rss=1
#immunity #convalescent #omicron #ba1 #ba2 #BA4
[Comment] Real-world #effectiveness of #nirmatrelvir–ritonavir against #BA4 and #BA5 #omicron #SARS-CoV-2 #variants https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00056-7/fulltext?rss=yes
#effectiveness #nirmatrelvir #BA4 #BA5 #omicron #sars #variants
[Articles] Real-world use of #nirmatrelvir–ritonavir in #outpatients with #COVID19 during the era of #omicron #variants including #BA4 and #BA5 in #Colorado, #USA: a retrospective cohort study https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00011-7/fulltext?rss=yes
#nirmatrelvir #outpatients #COVID19 #omicron #variants #BA4 #BA5 #Colorado #usa
#Neutralization of #BA4–BA.5, #BA46, #BA275.2, #BQ11, and #XBB.1 with Bivalent #Vaccine, NEJM: https://www.nejm.org/doi/full/10.1056/NEJMc2214916?query=TOC&cid=NEJM%20eToc,%20January%2026,%202023%20DM1931502_NEJM_Non_Subscriber&bid=1379403247
#neutralization #BA4 #ba46 #ba275 #bq11 #xbb #vaccine
#Protection conferred by #Delta and #BA1 / #BA2 #infection against #BA4 / #BA5 infection and #hospitalization: A Retrospective Cohort Study, The Journal of Infectious Diseases, jiad003, https://doi.org/10.1093/infdis/jiad003
#protection #delta #ba1 #ba2 #infection #BA4 #BA5 #Hospitalization
Li, M., Ren, Y., Aw, Z.Q. et al. Broadly neutralizing and protective #nanobodies against #SARS-CoV-2 #Omicron subvariants #BA1, #BA2, and #BA4/5 and diverse #sarbecoviruses. Nat Commun 13, 7957 (2022). https://doi.org/10.1038/s41467-022-35642-2
#Nanobodies #sars #omicron #ba1 #ba2 #BA4 #sarbecoviruses
Das ist, unabhängig von der/n Diskussion/Fragen um die immer noch nicht bekannte zeitliche Verfügbarkeit der bereits zugelassenen [Original & Omicron #BA4/#BA5]-Booster hochinteressant & positiv, da die Daten in relevantem Ausmass übertragbar sein dürften. 2/7
Es ist zum wahnsinnig werden. Ich habe eine schwere Diabetes Typ 2 und einen BMI über 40 und muss JEDESMAL über den Booster mit dem impfarzt diskutieren und auf die #impfung bestehen.. das war so beim zweiten Booster und auch eben gerade bei der Impfung gegen #BA4 #BA5. SCH... #STIKO. @minkorrekt @HOAXILLA
So, hier nun das Update: nachdem ich keinen Arzt gefunden hatte der mich ein 5. Mal impfen wollte, ging es nun endlich problemlos im #Impfzentrum #Bremen. Das ausschlaggebende Kriterium für war letztlich nur - 6 Monate Abstand zur vorherigen Impfung, sonst nichts (3 Monate zur Infektion wenn ich es richtig verstanden habe, aber da bin ich nicht sicher da nicht betroffen). #CovidIsNotOver #ImpfenSchützt #bivalent #BA4 #BA5 #Biontech #Moderna #ImpftDieKinder #FünfteImpfung #Booster
#booster #funfteimpfung #impftdiekinder #moderna #BioNTech #BA5 #BA4 #bivalent #impfenschutzt #CovidIsNotOver #bremen #Impfzentrum
Ju, B., Fan, Q., Wang, M. et al. #Antigenic sin of wild-type #SARS-CoV-2 #vaccine shapes poor cross- #neutralization of #BA4/5/2.75 #subvariants in #BA2 breakthrough infections. Nat Commun 13, 7120 (2022). https://doi.org/10.1038/s41467-022-34400-8
#antigenic #sars #vaccine #neutralization #BA4 #subvariants #ba2