“There was a small but significant increase in peak neutralizing antibody responses against #Omicron #BA5 and #XBB15 following the first #bivalent #booster, but no significant increase in peak titers following the second bivalent booster. Omicron-specific #neutralizing titers remained low after both doses of the BA.5 bivalent booster.” https://mstdn.social/@erictopol/110894423101207690
#omicron #BA5 #xbb15 #bivalent #booster #neutralizing
[Articles] Relative #effectiveness of monovalent and bivalent #mRNA #boosters in preventing severe #COVID19 due to #omicron #BA5 infection up to 4 months post-administration in people aged 60 years or older in #Italy: a retrospective matched cohort study https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00374-2/fulltext?rss=yes #epidemiology #health #policy #vaccine #vaccination #elderly #medicine #research
#effectiveness #mrna #boosters #COVID19 #omicron #BA5 #Italy #epidemiology #health #policy #vaccine #vaccination #elderly #medicine #research
Associations of #COVID19 #symptoms with #omicron subvariants #BA2 and #BA5, host status, and #clinical outcomes in #Japan: a registry-based observational study - Lancet ID.: https://doi.org/10.1016/S1473-3099(23)00271-2 #epidemic #pandemic #epidemiology
#COVID19 #symptoms #omicron #ba2 #BA5 #clinical #japan #epidemic #pandemic #epidemiology
“Hybrid immunity against #XBB was lower than against #BA4 or #BA5, especially in adolescents. Early #vaccination of previously uninfected children before their first #SARSCoV2 exposure could potentially strengthen population immunity resilience against future variants.”
#xbb #BA4 #BA5 #vaccination #SarsCoV2
BNT162b2 vaccine protection against omicron and effect of previous infection variant and vaccination sequence among children and adolescents in Singapore: a population-based cohort study - The Lancet Child & Adolescent Health https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(23)00101-3/fulltext “In previously infected children and adolescents, #BNT162b2 #vaccination provided additional protection against omicron #BA4 or #BA5 and #XBB #variants compared with those who remained #unvaccinated.
#BNT162b2 #vaccination #BA4 #BA5 #xbb #variants #unvaccinated
#mRNA #vaccines and hybrid #immunity use different B cell #germlines against #Omicron #BA4 and #BA5 https://www.nature.com/articles/s41467-023-37422-y
#mrna #vaccines #immunity #germlines #omicron #BA4 #BA5
Weiß jemand aus der Medibubble, ob eine sechste #impfung mit einem angepassten Impfstoff #BA5 nachweislich Vorteile bringen würde, auch angesichts neuester Varianten wie #xbb116
Beim blauen Vogel kursiert gerade eine Studie aus Kanada, wonach der Nutzen sehr gering sein soll.
#impfung #BA5 #xbb116 #COVID19 #COVID
Protective immunity of #SARSCoV2 #infection & vaccines against medically attended symptomatic #omicron #BA4, #BA5, and #XBB reinfections in Singapore: a national cohort study
"Protection against XBB reinfection conferred by a previous omicron infection with vaccination was lower and waned faster than protection against BA.4 or BA.5 reinfection, which is indicative of the greater immune evasiveness of the XBB sublineage"
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00060-9/fulltext
#sarscov2 #infection #omicron #BA4 #BA5 #xbb #SARS2 #variants #covid19
[Articles] Protective #immunity of #SARS-CoV-2 #infection and #vaccines against medically attended symptomatic #omicron #BA4, #BA5, and #XBB #reinfections in #Singapore: a national cohort study https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00060-9/fulltext?rss=yes
#immunity #sars #infection #vaccines #omicron #BA4 #BA5 #xbb #Reinfections #singapore
Associations of #COVID19 Symptoms with #Omicron #Subvariants #BA2 and #BA5, Host Status, and Clinical Outcomes: A Registry-Based Observational Study in Sapporo, Japan
- BA.5 infection associated with higher symptom burden than BA.2
- Omicron breakthrough-infected individuals with ≥ 3 vaccinations or previous infection were less likely to exhibit systemic symptoms, but more likely to exhibit upper respiratory symptoms.
https://www.medrxiv.org/content/10.1101/2023.02.02.23285393v1
#covid19 #omicron #subvariants #ba2 #BA5 #sarscov2 #SARS2
Associations of #COVID19 Symptoms with #Omicron #Subvariants #BA2 and #BA5, Host Status, and Clinical Outcomes: A Registry-Based Observational Study in Sapporo, Japan
- BA.5 infection associated with higher symptom burden than BA.2
- Omicron breakthrough-infected individuals with ≥ 3 vaccinations or previous infection were less likely to exhibit systemic symptoms, but more likely to exhibit upper respiratory symptoms.
https://www.medrxiv.org/content/10.1101/2023.02.02.23285393v1
#COVID19 #Omicron #subvariants #ba2 #BA5 #SarsCoV2 #SARS2
[Comment] Real-world #effectiveness of #nirmatrelvir–ritonavir against #BA4 and #BA5 #omicron #SARS-CoV-2 #variants https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00056-7/fulltext?rss=yes
#effectiveness #nirmatrelvir #BA4 #BA5 #omicron #sars #variants
[Articles] Real-world use of #nirmatrelvir–ritonavir in #outpatients with #COVID19 during the era of #omicron #variants including #BA4 and #BA5 in #Colorado, #USA: a retrospective cohort study https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00011-7/fulltext?rss=yes
#nirmatrelvir #outpatients #COVID19 #omicron #variants #BA4 #BA5 #Colorado #usa
Comparative #Effectiveness of #COVID19 #Vaccines in Preventing #Infections and Disease #Progression from #SARS-CoV-2 #Omicron #BA5 and #BA2, #Portugal https://wwwnc.cdc.gov/eid/article/29/3/22-1367_article
#effectiveness #COVID19 #vaccines #infections #progression #sars #omicron #BA5 #ba2 #portugal
#Seroprevalence of Specific #SARS-CoV-2 #Antibodies during #Omicron #BA5 Wave, #Portugal, April–June 2022 https://wwwnc.cdc.gov/eid/article/29/3/22-1546_article
#seroprevalence #sars #antibodies #omicron #BA5 #portugal
#SARS-CoV-2 #Incubation Period during the #Omicron #BA5–Dominant Period in #Japan https://wwwnc.cdc.gov/eid/article/29/3/22-1360_article
#sars #incubation #omicron #BA5 #japan
RT @NFMai@twitter.com
Die #Omicron-Subvariante #BA5 schädigt Kardiomyozyten stärker als BA.1 und ähnlich stark wie die #Delta-Variante.
#SARSCoV2 bleibt also zerstörerisch. Das Aufheben aller Maßnahmen, z.B. auch der #Maskenpflicht in Pflegeeinrichtungen, scheint mir nicht allzu vernünftig zu sein. https://twitter.com/RWittenbrink/status/1618602094877093891
#omicron #BA5 #Delta #SARSCOV2 #Maskenpflicht
Link-Gelles R, Ciesla AA, Roper LE, et al. Early #Estimates of Bivalent #mRNA #Booster Dose Vaccine #Effectiveness in Preventing Symptomatic #SARS-CoV-2 #Infection Attributable to #Omicron #BA5– and #XBB/XBB.1.5–Related Sublineages Among Immunocompetent Adults — Increasing Community Access to Testing Program, #USA, Dec 22–Jan 23. MMWR Morb Mortal Wkly Rep. ePub: 25 January 2023. DOI: http://dx.doi.org/10.15585/mmwr.mm7205e1.
#estimates #mrna #booster #effectiveness #sars #infection #omicron #BA5 #xbb #usa
Frage an die #Covid #Vaccination Fachleute hier in der #Medibubble: Teenager dreifach geimpft mit #Covid19 #Durchbruchsinfektion Anfang Juli 22 (daher vermutlich #BA5 ?): seht ihr einen Nutzen für die vierte #Impfung mit BA5 Impfstoff um jetzt im Winter noch etwas mehr Schutz zu haben oder sollte die Immunität nach Durchbruchsimpfung ausreichen und der #Booster keine Verbesserung mehr bringen? Hab zu dem Thema noch keine eindeutige Meinung gefunden🤷♀️
Bitte gern teilen für Reichweite, danke 🙏🏻
#covid #vaccination #medibubble #COVID19 #durchbruchsinfektion #BA5 #impfung #booster
#Epidemiology of #SARS-CoV-2 #Omicron #BA5 Infections, #Macau, June–July 2022 https://wwwnc.cdc.gov/eid/article/29/2/22-1243_article
#epidemiology #sars #omicron #BA5 #macau