Alexander Rogge · @alexanderrogge
42 followers · 1651 posts · Server brighteon.socialDeborah Byrd - Life’s building blocks found in Orion Nebula:
https://earthsky.org/space/lifes-building-blocks-found-in-orion-nebula/
#OrionNebula #OrionBar #Biomarker #Carbon #MethylCation #CH3Plus #D203506 #RedDwarf #JamesWebb #SpaceTelescope #JWST #NASA #OrganicChemistry #Chemistry #Astronomy
#OrionNebula #OrionBar #Biomarker #carbon #MethylCation #CH3Plus #D203506 #reddwarf #JamesWebb #SpaceTelescope #JWST #NASA #OrganicChemistry #chemistry #astronomy
Javier Díaz-Nido · @Javier_DN
171 followers · 359 posts · Server red.niboe.infoAstrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer’s disease
Aβ was associated with increased plasma phosphorylated tau only in individuals positive for astrocyte reactivity (Ast+).
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Neuroinflammation #BetaAmyloid #AmyloidPlaques #Tau #NeurofibrillaryTangles #ReactiveAstrocytes #Astrocytes #Glia #GFAP #Biomarker #Alzheimer #Biomedicine #Health
#health #biomedicine #Alzheimer #Biomarker #GFAP #Glia #astrocytes #ReactiveAstrocytes #NeurofibrillaryTangles #Tau #AmyloidPlaques #BetaAmyloid #neuroinflammation #Neurodegeneration #NeurodegenerativeDiseases #NeurologicalDiseases #neurology #brain #neuroscience
Monica Di, PhD :verified: · @NeuroDrugDoc
548 followers · 852 posts · Server med-mastodon.com#FDA just approved Qalsody (tofersen) for #ALS with #SOD1 mutation (~2% of ALS cases), based on a ⬇️ of the #biomarker neurofilament (NFL) in the plasma.
🔹 ALS is a progressive neurodegenerative disorder, attacking nerve cells that control voluntary muscles (e.g., breathing)
🔹 Qalsody is given intrathecally (in the spine) with 3 initial doses at 14-day intervals and maintenance every 28 days
🔹 Most common side effects were pain, fatigue, joint pain, ⬆️ white blood cells in the CSF, and muscle pain
Schlafmedizin+Schlafforschung · @Intersom_Koeln
4 followers · 51 posts · Server nrw.social
#Post-Covid: Forschende identifizieren #Biomarker bei Betroffenen. Warum jemand das Syndrom entwickelt, bleibt allerdings weiterhin unklar. https://www.scinexx.de/news/medizin/post-covid-zeigt-sich-an-der-dna/
Tim Kaiser · @tkaiser
321 followers · 612 posts · Server fediscience.orgRT @EikoFried
1/4 If you read one #depression #biomarker paper this year, read this one by Nils & the gang. They looked at a large sample of depressed and healthy participants, investigating numerous features (neuro, genetics, etc) in 2.4 million #MachineLearing models. https://twitter.com/NilsRWinter/status/1633458191643312128
#machinelearing #Biomarker #depression
Colin-Roy Hunter · @criquaer
276 followers · 2764 posts · Server mastodon.lol“Given how conservative the #NIH is, any talk about a #biomarker is noteworthy. The NIH, though, wasn’t exactly out on the skinny branches with that possibility. The studies were big enough (>200 people per study) and rigorous enough so that any common findings would automatically bring up talk of a biomarker.”
#pwME #MyalgicEncephalomyelitis #ChronicFatigueSyndrome #MECFS
https://www.healthrising.org/blog/2023/02/10/gut-biomarker-chronic-fatigue-syndrome-pt-1/
#nih #Biomarker #pwme #MyalgicEncephalomyelitis #ChronicFatigueSyndrome #mecfs
Johannes · @johannes_lehmann
155 followers · 266 posts · Server fediscience.orgPick a publication on cellular #senescence at random and it likely describes something completely new: a hitherto unknown #biomarker to rule them all, a suspiciously overlooked key contribution to age-associated diseases or yet another essential molecular cogwheel. So it’s refreshing to read a manuscript critically analysing previous findings:
Battaglia et al.
Lost in HELLS: disentangling the mystery of SALNR existence in senescence cellular models
https://www.biorxiv.org/content/10.1101/2023.02.03.526712v1
#biorxiv
#biorxiv #Biomarker #senescence
dystobot · @dystobot
5 followers · 2112 posts · Server med-mastodon.com[Automatic repost https://twitter.com/dystobot/status/1621479899197235201]
RT @ANA_journals: #GraphicalAbstracts DystoniaBoTXNet: Novel Neural Network #Biomarker of #Botulinum Toxin Efficacy in Isolated #Dystonia https://t.co/pqy6DOScog @TheNewANA1 @WileyNeuro @movedisorder https://t.co/kAe541xipR
#graphicalabstracts #Biomarker #botulinum #dystonia
Colin-Roy Hunter · @criquaer
224 followers · 1891 posts · Server mastodon.lol
#PwME may be interested in this by #HealthRising:
‘“What about #MECFS, #FM, and similar diseases?”. Given the close physiological overlap between ME/CFS/FM and #LongCovid, my question is: why would a similar #biomarker not apply to these diseases as well? Dr. Nath may be right – if you solve one of these mystery diseases, you’ll probably be well on the way to solving the others.
https://www.healthrising.org/blog/2022/12/22/explosion-therapeutics-long-covid-biomarker-chronic-fatigue-fibromyalgia/
#pwme #healthrising #mecfs #fm #LongCovid #Biomarker
Javier Díaz-Nido · @Javier_DN
131 followers · 137 posts · Server red.niboe.info
Spinal Cord Abnormalities Correlate With Disease Severity in FA
Results show utility of MRI as biomarker in tracking disease progression
Damage to the spinal dorsal column seems developmental whereas damage of the corticospinal tract may be both developmental and degenerative in origin.
#Neuroscience #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Neurodevelopment #NeurodevelopmentalDisorders #Ataxia #FriedreichAtaxia #SpinalCord #Neurogenetics #NeurogeneticDiseases #GeneticDiseases #RareDiseases
#MagneticResonanceImaging #MRI #Biomarker #BrainImaging
https://friedreichsataxianews.com/news/fa-spinal-cord-abnormalities-correlate-with-disease-severity/
#BrainImaging #Biomarker #mri #MagneticResonanceImaging #RareDiseases #GeneticDiseases #NeurogeneticDiseases #neurogenetics #SpinalCord #FriedreichAtaxia #ataxia #neurodevelopmentaldisorders #neurodevelopment #Neurodegeneration #NeurodegenerativeDiseases #NeurologicalDiseases #neurology #neuroscience
dystobot · @dystobot
2 followers · 110 posts · Server med-mastodon.com[Automatic repost from the bird https://twitter.com/dystobot/status/1604879274174996483]
RT @SimonyanLab: #DystoniaBoTXNet and its treatment #biomarker is the first #AI platform to provide objective, accurate, generalizable, fast, and cost-effective estimates of #BotulinumToxin efficacy from individual raw structural brain MRIs of patients with focal #dystonia.
#dystoniabotxnet #Biomarker #ai #botulinumtoxin #dystonia
Three Percent Earth Foundation · @threepercentearth
26 followers · 80 posts · Server mastodon.greenForté et.al., in a 2021 study measured #clinical #biomarker levels among a #farmworker cohort in Northern #Thailand who use #pesticides. CBC & urine findings were consistent w/exposures to #chlorpyrifos #metal-axyl & #methomyl
1. Stat. signif. AChE decrease w/methomyl exposure
2. Stat. signif. increases in #eosinophil, urine creatinine, & MCV
3. Stat. signif. decreases in #monocytes #RBC & #WBC counts, and serum Ca2+
4. self-rptd 'dizziness' 'tremors'
5. Non-Std. PPE used
https://onlinelibrary.wiley.com/doi/epdf/10.1002/1348-9585.12222
#clinical #Biomarker #farmworker #Thailand #pesticides #chlorpyrifos #metal #methomyl #eosinophil #monocytes #rbc #WBC
Ramesh Glückler · @rglueckler
102 followers · 24 posts · Server fediscience.org🔥 Interested in long-term #fire reconstructions & #paleoecology? 🔥
Follow this group and mention it in your toots to quickly share content with like-minded folks:
@paleofire
#wildfire #disturbance #ecology #geography #pyrogeography #archaeology #palynology #lake #marine #ice #soil #core #sediment #peat #dendrochronology #firescars #reconstruction #forest #fuel #proxy #geoscience #charcoal #biomarker #bpca #levoglucosan #pahs #pollen #carbon #blackcarbon #fireregime #holocene
#Holocene #fireregime #blackcarbon #carbon #Pollen #pahs #levoglucosan #bpca #Biomarker #charcoal #geoscience #proxy #fuel #forest #reconstruction #firescars #dendrochronology #peat #sediment #core #soil #ice #marine #lake #palynology #archaeology #pyrogeography #geography #ecology #disturbance #wildfire #paleoecology #fire
Colin-Roy Hunter · @criquaer
32 followers · 242 posts · Server mastodon.lol
A #neurology professor in Berlin, Germany, has discovered a #biomarker for those rare individuals who develop #PostVacSyndrome #PostVaccinationSyndrome. The link is to a long article in #German. #LongCovid #Covid #Covid19 #pwME
#neurology #Biomarker #POSTVACSYNDROME #postvaccinationsyndrome #german #LongCovid #covid #COVID19 #pwme
Lorenzo Gerratana · @LGerratana
10 followers · 8 posts · Server med-mastodon.com
CDK4/6i beyond progression will have a role in metastatic #BreastCancer, but a correct #Biomarker implementation will be crucial. Intriguing #LiquidBiopsy data suggest a potential added benefit in ESR1 mutated #MBC. Similar to PADA-1, unlike MAINTAIN #ctDNA #PrecisionMedicine
#breastcancer #Biomarker #LiquidBiopsy #MBC #ctDNA #precisionmedicine
