Clearly, there is still much to learn about this corner of the dark genome defined by HEATR5 proteins and their co-factors.

#Biorxiv #Preprint #MembraneTraffic #DarkGenome #DarkProteome #RareDisease #AlphaFold #AlphaFold2 #ProteinPrediction #Golgi #Clathrin #CellBiology #biochemistry #Bioscience

@kristinHenry Since it's #SciArtPortfolioWeek, I put together a gallery of some #Neuroscience and #CellBiology videos I've made using neuVid: https://github.com/connectome-neuprint/neuVid/blob/master/documentation/gallery.md

Hiring a postdoc to study host-microbe interactions! See flyer and shropshirelab.com for details, and share with anyone that may be interested!

@jobsecoevo #ScienceJobs #PostdocJob #EcoEvo #CellBiology #Genetics #Symbiosis #Bacteria #Insects #Wolbachia #Drosophila

Interested in what we learn from this. #Science is cool!

https://www.geekwire.com/2023/allen-institute-stem-cells-space/

#StemCells
#ISPCs
#CellBiology
#NASA
#Microgravity
#Seattle
#AllenInstitute

Interested in what we learn from this. #Science is cool!

https://www.geekwire.com/2023/allen-institute-stem-cells-space/

#StemCells
#ISPCs
#CellBiology
#NASA
#Microgravity
#Seattle
#AllenInstitute

#IDmastodon #Cellbiology #Immunology #Adaptiveimmunity Understanding Role of Ectocytosis & endocytosis in viral infections & viral clearances @sciencemagazine
📌https://www.science.org/doi/epdf/10.1126/science.abp893
@cellpress
📌 https://www.sciencedirect.com/science/article/pii/S0966842X22003420

The Scientific Computing group at #HHMIJanelia seeks a software engineer, to work on large-scale electron #microscopy reconstruction and analysis. Come work at the forefront of #imaging and #OpenScience with applications in #Neuroscience and #CellBiology. Janelia welcomes and values diversity, and encourages applications from people of all backgrounds, including people of color and members of groups traditionally underrepresented in science. (#FediHire, #FediHired)

https://hhmi.wd1.myworkdayjobs.com/en-US/External/job/Scientific-Computing-Software-Engineer_R-1972

Folded membrane microdomains between the cuticle and epidermis called 'meisosomes' have a role in maintaining and patterning these structures in #CElegans. and its connection with the extracellular matrix. #CellBiology https://elifesciences.org/articles/75906?utm_source=mastodon&utm_medium=social&utm_campaign=organic

“Histone modifications are known to have long-term residual timing,” says Li. The alteration can persist, particularly in lung cells which have a longer lifespan than many other kinds of cells, he adds. Therefore, these epigenetic changes could be the molecular basis of long COVID, and further work could pave the way for therapeutic interventions, he says.”

https://www.the-scientist.com/news-opinion/covid-19-infections-may-reshape-genetic-landscape-71045

#COVID
#COVID19
#Science
#Biology
#Research
#Epigenetics
#CellBiology
#MolecularBiology

@Nature #cellimmunity #Immunology #CellBiology #SARSCoV2 both induces #DNA damage and impairs its repair, ultimately causing cells to age and spread inflammation.
📌 https://www.nature.com/articles/s41556-023-01097-w
📌 https://www.nature.com/articles/s41556-023-01096-x
📌 https://www.nature.com/search?q=Covid19&journal=

#IDMastodon @Sciam #Cellbiology #iimmunology #COVID19 Finding the best shot for An ideal pancoronavirus vaccine would protect us from all four of its genera—alpha, beta, gamma, and delta
https://www.science.org/content/article/vaccines-can-protect-against-many-coronaviruses-could-prevent-another-pandemic?utm_campaign=SciMag&utm_source=Twitter&utm_medium=ownedSocial

#Cellbiology #IDMastodon #Immunology @aaas #Clinicalreview Understanding the association between The extracellular matrix and the #immunesystem work and how immune cells dictate ECM complexity.
https://www.science.org/doi/epdf/10.1126/science.abp8964

#IDMaston #CellBiology #immunology @PLOS @biorxivpreprint unertanding the occurrence of cytokine storm caused by #SARSCoV2 infection
#SarsCoV2 ORF8 a secretory protein that’s associated with cytokine release & Unconventional secretion of unglycosylated ORF8 is critical for the cytokine storm during #SARSCoV2 infection
📌 https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1011128
📌 https://www.biorxiv.org/content/10.1101/2021.12.03.471057v2.full.pdf

#Cellbiology Decoding how two structurally similar proteins support #autophagy, a form of cellular self-maintenance that often becomes compromised in cancer, neurodegeneration, and other conditions. @SciSignal
https://www.science.org/doi/10.1126/scisignal.abo4457

Altered Speech May Be the First Sign of Parkinson's Disease:
Researchers attempted to identify early symptoms of Parkinson's disease using voice data. In their study, the researchers used artificial intelligence (AI) to analyze and assess speech signals, where calculations are done and diagnoses made in seconds rather than hours

https://www.mdpi.com/2076-3417/12/22/11601

#immunology #molcularbiology #CellBiology #cellularBiology #Parkinsons #parkinsondisease #neurology #scientificresearch

Beautiful #DevBio work from my #IBDM Colleagues 👇

Congrats to Rosanna Dono, Thomas Legier, Diane Rattier, Flavio Maina 👏 🎉

----------------

RT @FlavioMaina@twitter.com

Proud of our latest paper @NatureComms
on studies headed by Rosanna Dono in the lab, reporting that Epithelial disruption drives mesendoderm differentiation in hIPSCs by enabling TGF-β protein sensing. See: https://rdcu.be/c3Uql

#NatureCommunications #StemCells #hIPSCs #CellBiology

5 years ago, we published my favorite (so far) science of my career @cellcellpress! It has, and still is, leading us into new and unknown territory! Excited to put out some follow up work soon that sheds some light on the function of Arc intercellular signaling...AND data on other genes that have retained similar virus-like biology, with implications for cancer and neurological diseases.

#neuroscience #cellbiology #science
https://www.sciencedirect.com/science/article/pii/S0092867417315040

RT @TheAnaJanic@twitter.com

Become a #PrincipalInvestigator at the Dept of Medicine and Life Sciences at Pompeu Fabra University @the_prbb@twitter.com @UPFbiomed@twitter.com @UPFBarcelona@twitter.com. We're looking for a passionate scientist with strong track record in #CellBiology

👉 Read more & apply by February 14
https://www.upf.edu/web/biomed/TTCellBio2023

🐦🔗: https://twitter.com/TheAnaJanic/status/1612941236788203521

RT @MAG2ART@twitter.com

A Golgi apparatus protein in a cell videoed through a microscope. The Golgi is saturated to show the vesicles trafficking around the cell. #CellBiology

We're hiring a postdoc to study host-microbe interactions! Our integrative research program studies how the world's most common bacterial endosymbiont has become so successful. Much of it is to do with the bacteria's ability to make its host's sex lives all about them. If you think this sounds interesting, consider applying! Details are here: https://shropshirelab.com/job/postdoctoral-scholar-of-host-microbe-interactions/.
@jobsecoevo #ScienceJobs #PostdocJob #EcoEvo #CellBiology #Genetics #Symbiosis #Bacteria #Insects #Wolbachia #Drosophila