Julien Delpierre · @JulienDelpierre
254 followers · 248 posts · Server qoto.org

New paper from the Zerial Lab!

My colleagues and I have shown that apical projections across the bile canaliculi are load-bearing structures. These structures contribute to sustaining the anisotropic of the nascent tube under increased intraluminal during . These structures are supported by adherens and sealed by tight junctions.
I believe only @nunopmartins is here but if I am mistaken please tag any other author.

rupress.org/jcb/article/222/4/

#growth #junctions #CellPolarity #pressure #development #cellbiology #actomyosin #tubulogenesis #liver

Last updated 3 years ago

Kay Schneitz · @kay
56 followers · 25 posts · Server mstdn.science
Julien Delpierre · @JulienDelpierre
180 followers · 214 posts · Server qoto.org

Not too bad .
I tried with hepatocyte polarity
galactica.org/?prompt=wiki+art
The AI nailed the principle of cell polarity and the description is pretty good.
I'm impressed that it got the "hepatic cord".
However, it completely missed the specifics of hepatocyte polarity: Hepatocytes have multiple basal and apical surfaces. Also, the fact that the apical surfaces are facing the gastrointestinal tract is not completely incorrect but a bit misleading.

#galactica #CellPolarity #ai #cellbiology

Last updated 3 years ago

Julien Delpierre · @JulienDelpierre
180 followers · 214 posts · Server qoto.org

Not too bad .
I tried with hepatocyte polarity
galactica.org/?prompt=wiki+art
The AI nailed the principle of cell polarity and the description is pretty good.
I'm impressed that it got the "hepatic cord" word out.
However, it completely missed the specifics of hepatocyte polarity: Hepatocytes have multiple basal and apical surfaces. Also, the fact that the apical surfaces are facing the gastrointestinal tract is not completely incorrect but a bit misleading.

#ai #cellbiology #galactica #CellPolarity

Last updated 3 years ago