TrangAston :verified: · @CastlTrAstonDrs
1387 followers · 2943 posts · Server med-mastodon.com
#IDMastodon @frontimmunol #Clinicalreviews #Pharmacogenetics & #Pharmacogenomics identified #tumornecrosisfactor as being associated with severe #COVID19
https://www.frontiersin.org/articles/10.3389/fphar.2023.1171404/full
Overview of The clustering in #TNF receptor superfamily signaling in Molecular #innateimmunity
https://www.frontiersin.org/articles/10.3389/fimmu.2023.1225704/full?utm_source=S-TWT&utm_medium=SNET&utm_campaign=ECO_FIMMU_XXXXXXXX_auto-dlvrit
#IDMastodon #Clinicalreviews #pharmacogenetics #pharmacogenomics #tumornecrosisfactor #COVID19 #TNF #innateimmunity
TrangAston :verified: · @CastlTrAstonDrs
1298 followers · 2593 posts · Server med-mastodon.com
#IDMastodon #viraimmunotherapy #Clinicalreviews on the current & future #Drugdevelopment for #COVID19 therapies as the emergence of new variants of #SARSCoV2, it is expedient that various therapeutics are researched & developed for the containment of #COVID19 .
#IDMastodon #viraimmunotherapy #Clinicalreviews #DrugDevelopment #COVID19 #SarsCoV2
TrangAston :verified: · @CastlTrAstonDrs
1224 followers · 2257 posts · Server med-mastodon.com
#IDMastodon #Immunology #Viralimmunology #Molecularbiology #ClinicalReviews In this study suggests variants of concern strains (VOC) of #SARSCoV2 underwent stronger positive selection in the S gene vs Variants of Interest (VOI )or other strains, which may have contributed to their higher prevalence in circulation
📌 https://academic.oup.com/mbe/advance-article/doi/10.1093/molbev/msad089/7117614?login=false#.ZDkcymxzCjE.twitter
#IDMastodon #immunology #viralimmunology #molecularbiology #Clinicalreviews #SarsCoV2
TrangAston :verified: · @CastlTrAstonDrs
1216 followers · 2220 posts · Server med-mastodon.com
#IDMastodon #mucosalimmunity #Immunology @BenHalePhD Excellent #Clinicalreviews #Autoantibodies targeting type I interferons: Prevalence, mechanisms of induction & association with viral disease susceptibility ,severe #COVID19 , influenza, or herpes (varicella-zoster virus, herpes simplex virus, cytomegalovirus )
📌 https://onlinelibrary.wiley.com/doi/epdf/10.1002/eji.202250164
📌 https://pubmed.ncbi.nlm.nih.gov/37027328/
📌 https://onlinelibrary.wiley.com/toc/15214141/0/ja
#IDMastodon #mucosalimmunity #immunology #Clinicalreviews #Autoantibodies #COVID19
TrangAston :verified: · @CastlTrAstonDrs
1181 followers · 1964 posts · Server med-mastodon.com
#IDMastodon this #Clinicalreviews illustrates the relationship between several comorbidities and #COVID19. Age related comorbidities such as Parkinson’s disease, cancer, diabetes, and cardiovascular diseases may lead to life-threatening illnesses in #SarsCoV2 infected patients
https://pubs.acs.org/doi/full/10.1021/acsptsci.2c00181#
#IDMastodon #Clinicalreviews #COVID19 #SarsCoV2
TrangAston :verified: · @CastlTrAstonDrs
1181 followers · 1964 posts · Server med-mastodon.com
#IDMastodon this #Clinicalreviews illustrates the relationship between several comorbidities and #COVID19. Age related comorbidities such as Parkinson’s disease, cancer, diabetes, and cardiovascular diseases may lead to life-threatening illnesses in #SarsCoV2 infected patients
#IDMastodon #Clinicalreviews #COVID19 #SarsCoV2
TrangAston :verified: · @CastlTrAstonDrs
1176 followers · 1922 posts · Server med-mastodon.com
#IDMastodon #PedsICU @jacionline #Clinicalreviews Inherited and acquired errors of type I interferon #immunity govern susceptibility to #COVID19 and #multisysteminflammatorysyndrome in children
📌 https://www.sciencedirect.com/science/article/pii/S0091674923001768?dgcid=author
📌 https://www.sciencedirect.com/journal/journal-of-allergy-and-clinical-immunology
#IDMastodon #PedsICU #Clinicalreviews #immunity #COVID19 #multisysteminflammatorysyndrome
TrangAston :verified: · @CastlTrAstonDrs
1167 followers · 1881 posts · Server med-mastodon.com
#IDMastodon #hemostasis #Immnunology #Clinicalreviews In patients with #COVID19, #antiphospholipid #antibodies may help identify an increased risk of #thrombosis and other adverse outcomes.
https://www.sciencedirect.com/science/article/pii/S2475037923000067#fig1
@RPTHjournal
https://www.sciencedirect.com/journal/research-and-practice-in-thrombosis-and-haemostasis/vol/7/issue/1
#IDMastodon #hemostasis #immnunology #Clinicalreviews #COVID19 #antiphospholipid #antibodies #thrombosis
TrangAston :verified: · @CastlTrAstonDrs
1134 followers · 1701 posts · Server med-mastodon.com
#IDMastodon #Immunology @FrontImmunol in these #ClinicalReviews encapsulates & provides vigorous discussions on the current & evolving state of #COVID19vaccines, their design ,development that will provide better immune protection, robust responses, variant-specificity.
https://www.frontiersin.org/research-topics/26259/innate-immune-responses-to-sars-cov-2-in-infected-and-vaccinated-individuals#overview
#IDMastodon #immunology #Clinicalreviews #COVID19vaccines
TrangAston :verified: · @CastlTrAstonDrs
1121 followers · 1657 posts · Server med-mastodon.com
Infections and #CardiovascularDisease #Clinicalreviews is to summarise tropical infections affecting the CV system. @JACCJournals
📌 https://www.jacc.org/doi/full/10.1016/j.jacc.2022.08.813
📌 https://www.jacc.org/toc/jacc/81/1
#CardiovascularDisease #Clinicalreviews
TrangAston :verified: · @CastlTrAstonDrs
1121 followers · 1656 posts · Server med-mastodon.com
#IDmastodon #Cardiomastodon #Clinicalreviews #SARSCoV2 Infection & #cardiovasculardiseases .Alterations in Circulating #miRNA Levels after Infection with #SARSCoV2 Could Contribute to the Development of Cardiovascular Diseases: What We Know So Far @IJMS_MDPI
📌 https://www.mdpi.com/1422-0067/24/3/2380
📌 https://www.mdpi.com/1422-0067/24/2
#IDMastodon #cardiomastodon #Clinicalreviews #SarsCoV2 #cardiovasculardiseases #miRNA
TrangAston :verified: · @CastlTrAstonDrs
1120 followers · 1653 posts · Server med-mastodon.com
#OncoPharm #Clinicalreviews New Insights @JExpMed: Bhullar & @Cosimo_Commisso discuss work by Chu & An et al ,describing the role of the tricyclic antidepressant nortriptyline in inhibiting fatty acid uptake & its potential repurposing as a cancer therapeutic agent
📌https://rupress.org/jem/article/220/3/e20222097/213851/Stopping-the-fat-Repurposing-an-antidepressant-for
📌 https://rupress.org/jem
📌 https://rupress.org/jem/issue/220/1
TrangAston :verified: · @CastlTrAstonDrs
1116 followers · 1641 posts · Server med-mastodon.com
#IDMastodon #Drugdevelopment #Mucosalimmunity @biorxivpreprint
Mucoactive drugs block #SARSCoV2 Infection
In this #Clinicalreviews indicates that Intact MCT reduces SARS-CoV-2 infection, and
its pharmacologic activation may be effective as an anti- #COVID19 treatment.
https://www.biorxiv.org/content/10.1101/2023.01.30.526308v1.full.pdf
#IDMastodon #DrugDevelopment #mucosalimmunity #SarsCoV2 #Clinicalreviews #COVID19
TrangAston :verified: · @CastlTrAstonDrs
1116 followers · 1641 posts · Server med-mastodon.com
#IDMastodon #Drugdevelopment #Mucosalimmunity Mucoactive drugs block #SARSCoV2 Infection
In this #Clinicalreviews indicates that Intact MCT reduces SARS-CoV-2 infection, and
its pharmacologic activation may be effective as an anti- #COVID19 treatment.
https://www.biorxiv.org/content/10.1101/2023.01.30.526308v1.full.pdf
#IDMastodon #DrugDevelopment #mucosalimmunity #SarsCoV2 #Clinicalreviews #COVID19
TrangAston :verified: · @CastlTrAstonDrs
1114 followers · 1636 posts · Server med-mastodon.com
#CardioMastodon #Clinicalreviews @VirusesMDPI #CardiacArrhythmias in #postCOVID19syndrome /#LongCovid Prevalence, Pathology, Diagnosis, and Treatment
📌 https://www.mdpi.com/1999-4915/15/2/389
📌 https://www.mdpi.com/1999-4915/15/1
#cardiomastodon #Clinicalreviews #cardiacarrhythmias #postcovid19syndrome
TrangAston :verified: · @CastlTrAstonDrs
1111 followers · 1621 posts · Server med-mastodon.com
#IDMastodon #ClinicalReviews @PLOS
Adjuvant Aggrenox therapy was not associated with significantly reduced #COVID19 severity or all-cause mortality .There.is currently insufficient evidence to justify the standard use of A Aggrenox in hospitalized #COVID19 patients
📌 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0274243
📌 https://journals.plos.org/plosone/search?filterStartDate=2022-12-01&filterEndDate=2023-01-31&q=Covid-19%20&page=2&utm_content=b&utm_campaign=ENG-467
📌 https://journals.plos.org/plosone/search?q=Covid-19%20&sortOrder=DATE_NEWEST_FIRST&page=1&utm_content=b&utm_campaign=ENG-
#IDMastodon #Clinicalreviews #COVID19
TrangAston :verified: · @CastlTrAstonDrs
1108 followers · 1593 posts · Server med-mastodon.com
#IDMastodon #LongCovid antiviral treatments #Clinicalreviews by @Aguirre1Gustavo
https://www.researchgate.net/publication/366412536_FIRST_PROTOCOL_AND_THERAPEUTIC_TEST_WITH_TENOFOVIR_DISOPROXILEMTRICITABINE_Truvada_or_generic_TO_ASSIST_THE_DIAGNOSIS_OF_VIRAL_PERSISTENCE_IN_POST-ACUTE_COVID_SYNDROME_PACS_OR_LONG_COVID
#IDMastodon #LongCovid #Clinicalreviews
TrangAston :verified: · @CastlTrAstonDrs
1107 followers · 1589 posts · Server med-mastodon.com
#IDMastodon #Immunology #LongCovidKids #Clinicalreviews #PedMastodon
children had many different naive T cells to fight #SARSCoV2 & made poor memory T cell responses to 🦠 after they had recovered .These data suggest that rapid clearance of 🦠 in children may compromise their cellular immunity & ability to resist reinfection.
https://www.news-medical.net/news/20230126/Childrene28099s-immune-systems-do-not-develop-e28098adaptivee28099-memory-to-protect-against-second-time-SARS-CoV-2-infection.aspx
#IDMastodon #immunology #LongCovidKids #Clinicalreviews #pedmastodon #SarsCoV2
TrangAston :verified: · @CastlTrAstonDrs
1102 followers · 1572 posts · Server med-mastodon.com
#IDMastodon #ClinicalReviews #molecularapproach #InnateImmunity #Drugdevelopment for #COVID19 Treatments in progress. What’s in & What’s out
@FrontImmunol
https://www.frontiersin.org/articles/10.3389/fimmu.2023.1125246/full?utm_source=S-TWT&utm_medium=SNET&utm_campaign=ECO_FIMMU_XXXXXXXX_auto-dlvrit
#IDMastodon #Clinicalreviews #molecularapproach #innateimmunity #DrugDevelopment #COVID19
TrangAston :verified: · @CastlTrAstonDrs
1086 followers · 1536 posts · Server med-mastodon.com
#IDMastodon #cardiomastadon This #Clinicalreviews will provide an overview on Post-#AcuteCOVID19Syndrome / #LongCovid related frequent cardiovascular manifestations, emphasizing consequences, proposed pathophysiology & clinical diagnostic manifestation strategy.
https://www.imrpress.com/journal/RCM/24/1/10.31083/j.rcm2401028/htm
#IDMastodon #cardiomastadon #Clinicalreviews #acutecovid19syndrome #LongCovid