🔍Small CoVariants.org Note🔍

Due to a bug, 'recombinants' as a category isn't showing up currently on #CoVariants. This may make it look like more 'other' are circulating until we get it fixed!

Apologies for any confusion & hopefully it'll be back soon!

@firefoxx66
More information on 23A (XBB.1.5) & its spread will become available in due course.

As always, http://CoVariants.org is open-source & we welcome your PRs & suggestions to add more studies & information to variant pages! (Or any error-catching!)
http://github.com/hodcroftlab/covariants

5/N

#23A #XBB15 #CoVariants #SARSCoV2

@firefoxx66 On the Per Country page (http://covariants.org/per-country), 23A (XBB.1.5) is already clearly visible in the USA, Canada, UK & Israel, & is starting to appear in smaller numbers in other countries, like Germany & Singapore. Remember, sequencing data is always a few weeks behind.

Finally, on the Shared Mutations page (https://covariants.org/shared-mutations), you can see how 23A's / XBB.1.5's Spike mutations compare to other VoC, including its Omicron family and 22F (XBB) parent.

4/N

#XBB15 #CoVariants

@firefoxx66 There's also a link to the 23A (XBB.1.5) @nextstrain focal build:
http://nextstrain.org/groups/neherlab/ncov/23A.Omicron

Here, we can zoom in on the clade & get a closer look at how 23A sequences are distributed around the world, & their diversity. 🌏🌎

3/N

#XBB15 #SARSCoV2 #CoVariants

@firefoxx66 As I covered earlier (see thread https://mstdn.science/@firefoxx66/109643027333486673), #23A (XBB.1.5) is descended from the recombinant 22F (XBB) variant, with some additional mutations.

On the 23A #CoVariants page (https://covariants.org/variants/23A.Omicron), you can read about some initial 23A (XBB.1.5) work on neutralizing titres, see a list of defining mutations, a plot of the variant growth, link to Aquaria protein viz, & see a list of other mutations present in the variant.

2/N

#XBB15 #SARSCoV2

🎉 CoVariants.org Update! 🎉

23A (XBB.1.5) is now available on #CoVariants! It's visible as part of Per Country & Per Variant plots, on the shared mutation page - and of course, has a page of its own.

This is in line with the recent addition of 23A (XBB.1.5) as a @nextstrain clade - read more on that in this tweet thread: https://twitter.com/nextstrain/status/1623723987707564034

1/N

#XBB15 #23A #nextstrain

More information on #22F / #XBB will become available in due course.
As always, #CoVariants http://CoVariants.org is open-source & we welcome your PRs & suggestions to add more studies & information to variant pages! (Or any error-catching!)

http://github.com/hodcroftlab/covariants

8/9

Finally, on the #CoVariants Shared Mutations page, you can see how #22F's / #XBB's Spike mutations compare to other VoC, including its Omicron family.

7/9

http://covariants.org/shared-mutations

On the #22F #CoVariants page, you can read about some initial 22F / #XBB work on neutralizing titres, see a list of defining mutations, a plot of the variant growth, link to Aquaria protein viz, & see a list of other mutations present in the variant.

https://covariants.org/variants/22E.Omicron

4/9

🎉http://CoVariants.org Update!🎉

22F (XBB) is now available on #CoVariants! It's visible as part of Per Country & Per Variant plots, on the shared mutation page - and of course, has a page of its own.

1/9

#XBB #22F #SARSCoV2 #COVID19 #variants