So #Pharmacometrics can help us understand how drugs behave in different people. The #DrinkMe model includes body weight - the bigger you are, the bigger your organs are (usually) and the more machinery you have for metabolizing substances like ethanol, so the slower you get drunk, and if you've eaten something, the alcohol will take longer to get into your system (although these are just two aspects of a very complex system).

I promised you #Beer! It's actually a pretty good example. PK describes what happens to the alcohol (ethanol) you consume between the glass and the bathroom, and PD describes what it does while it's circulating in your blood (quite a few things, including making you tipsy). Ethanol is a pretty interesting case, because it's eye-wateringly complex. The #DrinkMe simulation on Nick Holford's website is a fun interactive example of how it fits together! #PMx

http://holford.fmhs.auckland.ac.nz/research/ethanol