It's not just about the drugs themselves. #DrugDisease and #DiseaseProgression models are also an area in which #Pharmacometrics continues to have an impact - #FDA maintains a list the ones they've developed internally, including examples for #Alzheimers and #Diabetes, although there are many, many more.

https://www.fda.gov/about-fda/center-drug-evaluation-and-research-cder/division-pharmacometrics