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“Other viruses, such as Epstein-Barr virus (#EBV), are also thought to trigger ME/CFS, although the mechanisms are equally complex.

Like other human herpes viruses, EBV can hide out in the body, evading the immune system for years until stress or some other illness reactivates the virus.”

@mecfs #MEcfs #CFS #MyalgicE #PwME #MyalgicEncephalomyelitis #ChronicFatigueSyndrome #MyE #ME #millionsmissing #CFSME #CFIDS
#SEID #NeuroME

For #MS and #EBV and viruses in general #virus. Potential advances in therapeutics. https://open.substack.com/pub/gavingiovannoni/p/breaking-news-we-have-a-new-therapeutic?r=9ah0d&utm_campaign=post&utm_medium=email

Cross-reactive EBNA1 immunity targets alpha-crystallin B and is associated with #MultipleSclerosis | Science Advances https://www.science.org/doi/10.1126/sciadv.adg3032 “This study provides evidence for antibody cross-reactivity between EBNA1 and CRYAB and points to a similar cross-reactivity in T cells, further demonstrating the role of #EBV adaptive immune responses in #MS development”

Ein fantastischer neuer Übersichtsartikel über die Myalgische Enzephalomyelitis/Chronisches Fatigue-Syndrom (#MECFS).

#Leseempfehlung für alle in medizinischen Berufen.

#Covid19 #EBV #LongCovid

https://www.aerzteblatt.de/archiv/231286/Myalgische-Enzephalomyelitis-Chronisches-Fatigue-Syndrom-Interdisziplinaer-versorgen

“The “Chronic viral coinfections differentially affect the likelihood of developing long COVID” study came out of a very active group of long-COVID researchers.

They’ve been responsible for a number of findings, including that gut microbes are leaking into the blood, that systemic inflammation and profound immune dysregulation is present, that Paxlovid may be helpful, that exercise capacity is reduced, and that persistent immune activation is present.” #EBV #LongCovid

https://www.healthrising.org/blog/2023/05/03/epstein-barr-virus-reactivation-fatigue-brainfog-long-covid/

Persistent SARS-CoV-2 virus can cause acidosis, as can clotting and inflammation.

This acidosis can further increase clotting & inflammation while also affecting the immune system, increasing auto-immunity and decreasing its ability to control infections (like #COVID and #EBV).

Wie das Epstein-Barr-Virus Krebs auslöst. Ein virales Protein des EBV verursacht Brüche im elften Chromosom. #EBV #EpsteinBarr #Virus #Krebs #Chromosom
https://www.scinexx.de/news/medizin/wie-das-epstein-barr-virus-krebs-ausloest/

Investigation of #LongCOVID Prevalence and Its Relationship to Epstein-Barr #Virus #Reactivation

n=185

- long COVID symptoms: 30.3% (56/185)

- positive for #EBV #reactivation : 66.7% (20/30) of long COVID subjects versus 10% (2/20) of control subjects

"findings suggest that many long COVID symptoms may not be a direct result of the #SARSCoV2 virus but may be the result of #COVID19 inflammation-induced #EBV reactivation."

https://www.semanticscholar.org/paper/Investigation-of-Long-COVID-Prevalence-and-Its-to-Gold-Okyay/bd507fc46a8e8a05563c9b9d4fdd22f8acf9b2ca

#SARS2 #ViralReactivation

Well isn't this interesting....

Systematic review with meta-analysis of active herpesvirus infections in patients with #covid19 : Old players on the new field

"There was a 6 times higher chance for active #EBV infection in patients with severe #COVID19 than in non-COVID-19 controls (OR=6.45, 95% CI=1.09-38.13, p=0.040) "

https://www.sciencedirect.com/science/article/pii/S1201971223000371

#SARS2 #sarscov2

SciTechDaily - Breaking Bad: How a Virus Infecting 90% of the World’s Population Unleashes Cancer

"In a new paper, published April 12, 2023, in the journal Nature, researchers at University of California San Diego, UC San Diego Moores Cancer Center, and Ludwig Cancer Research at UC San Diego, describe for the first time how the virus exploits genomic weaknesses to cause cancer while reducing the body’s ability to suppress it."

https://scitechdaily.com/breaking-bad-how-a-virus-infecting-90-of-the-worlds-population-unleashes-cancer/

#EpsteinBarrVirus #EBV #Oncology

So much in this article:

“Unless the president of the United States would declare #Alzheimer's a national emergency … that, I’ve been told, is the only way this could be done.” — Alberto Ascherio

"Scientist who uncovered likely leading cause of MS (i.e., Epstein-Barr infection) wants to tackle #ALS next" https://www.statnews.com/2023/03/16/alberto-ascherio-multiple-sclerosis-als/

#MND #ELA #SLA #EBV

Fortunately, I had seen something like this before.

I had "mono" or #EBV in school. My post-COVID presentation was very similar. Relapsing/remitting symptoms triggered by stress which mostly means lack of sleep.

Remember the sleep disordered symptoms?

Outstanding. My symptoms were triggering my symptoms.

Analytic that I am, this set me down the path to figure out what was going on & how to mitigate my risks.

What I learned in the first two years shook me to my core & hasn't let go.

RT @ChantalBritt
Vor 3 Jahren ging ich abends unbeschwert und ohne Maske ans Chorkonzert. Ich wusste nicht, dass ich ein erhöhtes Risiko hatte, an #MECFS zu erkranken. Ich wusste nicht, dass sich einige Menschen von #SARS1, #MERS oder #EBV #NieErholt hatten.
3 Jahre #LongCovid in 18 Tweets
1/

RT @MondayNightIBD
#Back2Basics #IBDPoll1️⃣

🆓#CME👉🏼 http://bit.ly/3lZ0VV3

Which population with #IBD could benefit from testing for #EBV serology before starting #Thiopurines (AZA/ Mercaptopurine) , as it relates to the risk of thiopurines associated #Lymphoma

RT @MondayNightIBD
#Back2Basics #IBDPoll1️⃣

🆓#CME👉🏼 http://bit.ly/3lZ0VV3

Which population with #IBD could benefit from testing for #EBV serology before starting #Thiopurines (AZA/ Mercaptopurine) , as it relates to the risk of thiopurines associated #Lymphoma

RT @MondayNightIBD
#Back2Basics #IBDPoll1️⃣

🆓#CME👉🏼 http://bit.ly/3lZ0VV3

Which population with #IBD could benefit from testing for #EBV serology before starting #Thiopurines (AZA/ Mercaptopurine) , as it relates to the risk of thiopurines associated #Lymphoma

#Back2Basics #IBDPoll1️⃣

🆓#CME👉🏼 http://bit.ly/3lZ0VV3

Which population with #IBD could benefit from testing for #EBV serology before starting #Thiopurines (AZA/ Mercaptopurine) , as it relates to the risk of thiopurines associated #Lymphoma

New review article in The Lancet Neurology>

#EpsteinBarrVirus as a cause of #MultipleSclerosis: opportunities for prevention and therapy

https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(22)00471-9/fulltex

#EBV

@hannu_ikonen I can’t thank you enough for everything you do, and for publicly sharing all this information. I can’t figure out how to repay the people I credit with helping me stay Covid free so far, if not for the information that I’ve seen from people like you I would have been conned into being infected by now. I already have #MECFS from #EBV I can’t really live more disabled than I already am.

RT @Atarabio@twitter.com

Alongside @PierreFabre@twitter.com we're proud to announce @EMA_News@twitter.com approved our allogeneic T-cell therapy to treat adult & pediatric patients 2 years of age & older with r/r #EBV+ #PTLD, marking the first ever approval of an off-the-shelf T-cell immunotherapy. More: https://bit.ly/3HQF4rM

🐦🔗: https://twitter.com/Atarabio/status/1604809054383120385