"For the approach we have taken, we thought it should be sufficient to reference excellent published explanations (53, 54), however, recurrent misunderstanding during the review process of our work on this subject prompted us to demonstrate here with a simple example of how it works."

#Michaelis-Menten
#Enzyme kinetics...
#biophysics

https://www.biorxiv.org/content/10.1101/2023.08.29.555394v1

Unser neues Heft 3/2023 ist draußen!

Titel-Thema:
Wie altert das #Immunsystem?

Außerdem:
- #ChatGPT & #Wissenschaft;
- Ur-#Enzyme;
- #Chemotherapie-Resistenz;
- #Optogenetik;
- Expansions-#Mikroskopie;
- #DNA-Origami
- u.v.a.m.

Das ganze Heft online:
👉 https://www.laborjournal.de/rubric/aktuell/index.php

@davidschnettler and the Hollfelder-team have used #DirectedEvolution to breed new phosphotriesterases that could be useful for bioremediation or treatment of organophosphate intoxication. Active #enzyme variants were retrieved from large libraries packaged in tiny droplets on a #microfluidics platform.

Now in #jacs
https://pubs.acs.org/doi/full/10.1021/jacs.2c10673

Amin-umwandelnde #Enzyme sind Meister der asymmetrischen Synthese. Ein Team der Uni Greifswald entwickelte ein Selektions-System, mit dem man die besten Kandidaten für das Handling des jeweiligen Lieblings-Amins findet … Andrea Pitzschke stellt es vor: 👉 https://www.laborjournal.de/editorials/2650.php

Adenosine, a #biochemical that is found in cells and is essential for many processes. Adenosine is made up of an adenine nitrogenous base linked to a #ribose sugar #molecule. It is involved in the #biosynthesis and #replication of #DNA and #RNA, and is also a component of an #enzyme called S-adenosyl-L-methionine (SAM) and cyano-cobalamin (vitamin B-12). #Adenosine was once thought to only modify #cardiovascular #physiology, but now it is known to have many other effects on physiology.

2/8 In an unbiased way, Amy queried if any of 6 fatty acids regulate #androgen metabolism in several ways. Not just #enzyme transcript - rather direct #metabolism. Arachidonic acid (AA) gave the strongest signal and led to loss of the DHT precursor 5α-dione. @PCF_Science

My paper on the fabrication of an immobilized #enzyme reactor was featured on the cover of #AnalyticalMethods recently. You can read it here: https://pubs.rsc.org/en/content/articlehtml/2022/AY/D2AY00840H #bioanalytical #analyticalchemistry #chemistry #proteomics

My paper on the fabrication of an immobilized #enzyme reactor using formaldehyde or triethoxysilylbutryaldehyde was featured on the cover of #AnalyticalMethods Read it here: https://pubs.rsc.org/en/content/articlehtml/2022/AY/D2AY00840H #bioanalytical #chemistry #proteomics

Hello, Mastodon world! I am an assoc. prof of #biochemistry at San Diego State University #SDSU studying the kinetic, structural, and cellular consequences of #cancer -driving #enzyme mutants...with a focus on IDH and polymerases. I fight for diverse access to #STEM -- our #diversity is our superpower!

A #Plastic Eating #Enzyme: #Hope for #Recycling and Fighting #Pollution | #Researchers have identified and engineered an enzyme which can digest and consume some of our most commonly polluting plastics providing a hope for recycling...

https://www.scientificeuropean.co.uk/environment/a-plastic-eating-enzyme-hope-for-recycling-and-fighting-pollution/