PLOS Biology · @PLOSBiology
4642 followers · 716 posts · Server fediscience.org
The RNA-binding protein #FMRP binds the Csw/SHP2 transcript, in turn regulating presynaptic MAPK/ERK signaling & #neurotransmission. This mechanistically links two cognitive disorders; #NoonanSyndrome & #FragileX syndrome #PLOSBiology https://plos.io/3JjpqG0
#plosbiology #fragilex #noonansyndrome #neurotransmission #FMRP
PLOS Biology · @PLOSBiology
4626 followers · 698 posts · Server fediscience.org
The RNA-binding protein #FMRP binds the Csw/SHP2 transcript, in turn regulating presynaptic MAPK/ERK signaling & #neurotransmission. This mechanistically links two cognitive disorders; #NoonanSyndrome & #FragileX syndrome #PLOSBiology https://plos.io/3JjpqG0
#plosbiology #fragilex #noonansyndrome #neurotransmission #FMRP
PLOS Biology · @PLOSBiology
4625 followers · 694 posts · Server fediscience.org
The RNA-binding protein #FMRP binds the Csw/SHP2 transcript, in turn regulating presynaptic MAPK/ERK signaling & #neurotransmission. This mechanistically links two cognitive disorders; #NoonanSyndrome & #FragileX syndrome #PLOSBiology https://plos.io/3JjpqG0
#plosbiology #fragilex #noonansyndrome #neurotransmission #FMRP
Seth Thomas Scanlon · @ImmunoEditor
127 followers · 8 posts · Server mstdn.social
In #Science (@sciencemagazine) this week, the Hanahan lab shows that the #RNA-binding protein #FMRP enables #tumors to evade being attacked by #CD8TCells. It does so by both suppressing #CCL17 & promoting #Tregs via #IL33 & #M2 #macrophages via #PROS1 & #ExtracellularVesicles!
#rbp #cancerimmunology #extracellularvesicles #pros1 #macrophages #M2 #il33 #tregs #ccl17 #cd8tcells #tumors #FMRP #RNA #Science
Autism News International · @AutismNewsBot
158 followers · 5296 posts · Server aspiechattr.me
Fragile X neurons develop atypically in chimeric mice
https://www.spectrumnews.org/news/fragile-x-neurons-develop-atypically-in-chimeric-mice/
#fragileXsyndrome #mousemodels #autism #News #FMR1 #FMRP
#fragileXsyndrome #mousemodels #autism #news #FMR1 #FMRP
Autism News International · @AutismNewsBot
158 followers · 5296 posts · Server aspiechattr.me
The cloudy connection between fragile X and cancer
https://www.spectrumnews.org/news/the-cloudy-connection-between-fragile-x-and-cancer/
#intellectualdisability #tuberoussclerosis #fragileXsyndrome #autism #cancer #News #FMR1 #FMRP #PTEN #TSC1
#intellectualdisability #tuberoussclerosis #fragileXsyndrome #autism #cancer #news #FMR1 #FMRP #PTEN #TSC1
Autism News International · @AutismNewsBot
158 followers · 5296 posts · Server aspiechattr.me
Largest-yet fragile X mutation in mice confirms model’s shortcomings
https://www.spectrumnews.org/news/largest-yet-fragile-x-mutation-in-mice-confirms-models-shortcomings/
#fragileXsyndrome #geneexpression #epigenetics #mousemodels #autism #News #FMR1 #FMRP
#fragileXsyndrome #geneexpression #epigenetics #mousemodels #autism #news #FMR1 #FMRP
Autism News International · @AutismNewsBot
159 followers · 5296 posts · Server aspiechattr.me
Plethora of protein-making machines in neurons may underlie fragile X
https://www.spectrumnews.org/news/plethora-of-protein-making-machines-in-neurons-may-underlie-fragile-x/
#synapticplasticity #fragileXsyndrome #geneexpression #hippocampus #mousemodels #SFARIGene #autism #mGluR5 #News #FMR1 #FMRP
#synapticplasticity #fragileXsyndrome #geneexpression #hippocampus #mousemodels #SFARIGene #autism #mGluR5 #news #FMR1 #FMRP
Autism News International · @AutismNewsBot
159 followers · 5296 posts · Server aspiechattr.me
Portrait of a research field: astrocytes in autism
https://www.spectrumnews.org/features/deep-dive/portrait-of-a-research-field-astrocytes-in-autism/
#excitatorysignaling #inhibitorysignaling #signalingimbalance #fragileXsyndrome #postmortembrains #geneexpression #Rettsyndrome #environment #mousemodels #astrocytes #organoids #DeepDive #seizures #synapses #autism #MECP2 #FMR1 #FMRP #GABA
#excitatorysignaling #inhibitorysignaling #signalingimbalance #fragileXsyndrome #postmortembrains #geneexpression #Rettsyndrome #environment #mousemodels #astrocytes #organoids #DeepDive #seizures #synapses #autism #MECP2 #FMR1 #FMRP #GABA
Autism News International · @AutismNewsBot
159 followers · 5296 posts · Server aspiechattr.meA whisper of autism: Fragile X carriers and the autism phenotype
https://www.spectrumnews.org/opinion/viewpoint/a-whisper-of-autism-fragile-x-carriers-and-the-autism-phenotype/
#fragileXsyndrome #bipolardisorder #genetictesting #endophenotype #aripiprazole #depression #Viewpoint #anxiety #autism #FMR1 #FMRP
#fragileXsyndrome #bipolardisorder #genetictesting #endophenotype #aripiprazole #depression #Viewpoint #anxiety #autism #FMR1 #FMRP
Autism News International · @AutismNewsBot
159 followers · 5296 posts · Server aspiechattr.meLocation prompts fragile X protein to flip its function
https://www.spectrumnews.org/news/location-prompts-fragile-x-protein-to-flip-its-function/
#signalingimbalance #synapticplasticity #learningandmemory #fragileXsyndrome #hippocampus #seizures #synapses #autism #News #FMRP
#signalingimbalance #synapticplasticity #learningandmemory #fragileXsyndrome #hippocampus #seizures #synapses #autism #news #FMRP
Autism News International · @AutismNewsBot
159 followers · 5296 posts · Server aspiechattr.meFinding a path forward for fragile X drugs
https://www.spectrumnews.org/news/finding-a-path-forward-for-fragile-x-drugs/
#fragileXsyndrome #clinicaltrials #biomarkers #treatments #language #autism #News #FMR1 #FMRP #EEG
#fragileXsyndrome #ClinicalTrials #biomarkers #treatments #language #autism #news #FMR1 #FMRP #EEG
Autism News International · @AutismNewsBot
159 followers · 5296 posts · Server aspiechattr.meRemembering Steve Warren (1953-2021): A giant in the field of genetics
https://www.spectrumnews.org/opinion/viewpoint/remembering-steve-warren-1953-2021-a-giant-in-the-field-of-genetics/
#spokenversion #Viewpoint #fragileX #autism #FMR1 #FMRP
#spokenversion #Viewpoint #fragileX #autism #FMR1 #FMRP
Autism News International · @AutismNewsBot
159 followers · 5296 posts · Server aspiechattr.meMolecular overlap links tuberous sclerosis, fragile X
https://www.spectrumnews.org/news/molecular-overlap-links-tuberous-sclerosis-fragile-x/
#tuberoussclerosis #fragileXsyndrome #geneexpression #spokenversion #cerebellum #rapamycin #News #FMRP #TSC1
#tuberoussclerosis #fragileXsyndrome #geneexpression #spokenversion #cerebellum #rapamycin #news #FMRP #TSC1