Really enjoyed reading this review about the #structuralbiology of the interaction between diff classes of #nanobodies and the #SARSCoV2 #spike by Tang, Owens and Naismith (doi: 10.3390/v13112214). Very important insight: neutralisation can occur by interference with the S mechanics, as well as by competing with receptor binding. In the figure, the 3D model of the S at #FranklinInstitute showing a nb bound to the N343 glycan on the S RBD 😍 #glycotime