Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer’s disease
Aβ was associated with increased plasma phosphorylated tau only in individuals positive for astrocyte reactivity (Ast+).
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Neuroinflammation #BetaAmyloid #AmyloidPlaques #Tau #NeurofibrillaryTangles #ReactiveAstrocytes #Astrocytes #Glia #GFAP #Biomarker #Alzheimer #Biomedicine #Health
#health #biomedicine #Alzheimer #Biomarker #GFAP #Glia #astrocytes #ReactiveAstrocytes #NeurofibrillaryTangles #Tau #AmyloidPlaques #BetaAmyloid #neuroinflammation #Neurodegeneration #NeurodegenerativeDiseases #NeurologicalDiseases #neurology #brain #neuroscience
Identifican un biomarcador en sangre para predecir el desarrollo de Alzheimer en personas sanas
Un estudio desafía la noción de que la proteína amiloide es suficiente para desencadenar la enfermedad y respalda el papel de los astrocitos como un factor desencadenante.
#Neurociencia #Cerebro #Neurología #EnfermedadesNeurológicas #EnfermedadesNeurodegenerativas #Neurodegeneración #Demencia #Alzheimer #Tau #OvillosNeurofibrilares #Amiloide #BetaAmiloide #PlacasSeniles #Sinapsis #Biomarcador #GFAP #Astrocito #Glia #Biomedicina #Salud
#Salud #Biomedicina #Glia #Astrocito #GFAP #Biomarcador #Sinapsis #PlacasSeniles #BetaAmiloide #Amiloide #OvillosNeurofibrilares #Tau #Alzheimer #demencia #Neurodegeneración #EnfermedadesNeurodegenerativas #EnfermedadesNeurológicas #neurología #cerebro #neurociencia
Functional roles of reactive astrocytes in neuroinflammation and neurodegeneration
#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Neuroinflammation #Neuroimmunology #Neuroimmune #ReactiveAstrocytes #Astrocytes #Glia #Alzheimer #Parkinson #Biomedicine #Health
#health #biomedicine #parkinson #Alzheimer #Glia #astrocytes #ReactiveAstrocytes #Neuroimmune #neuroimmunology #neuroinflammation #Neurodegeneration #NeurodegenerativeDiseases #NeurologicalDiseases #neurology #brain #neuroscience
RT @DoctorPAF@twitter.com
Pleased to share our first pre-print.
We looked at the axon death molecule #SARM1 in myelinating #CNS and #PNS #Glia in 🐭and 🐟
Surprisingly we find SARM1 is present & functional in #oligodendrocytes but not in #Schwanncells and #satelliteglia
https://www.biorxiv.org/content/10.1101/2022.12.08.519209v1
🐦🔗: https://twitter.com/DoctorPAF/status/1602284664533966849
#satelliteglia #schwanncells #oligodendrocytes #Glia #pns #CNS #sarm1
Just made my way here but couldn’t find the academic fed/nerd central for #physicians #scientists
Hope I can connect with great people here interested in #pain #glia #research #medicine #WomenInMedicine #womeninstem #womeninscience
#physicians #scientists #pain #Glia #research #medicine #WomenInMedicine #womeninstem #womeninscience