Exploration of glycosyltransferases mutation status in cervical cancer reveals PARP14 as a potential prognostic marker
http://rd.springer.com/10.1007/s10719-023-10134-7
#Glycotime #Glycoconjugate

Exploration of glycosyltransferases mutation status in cervical cancer reveals PARP14 as a potential prognostic marker
http://link.springer.com/10.1007/s10719-023-10134-7
#Glycotime #Glycoconjugate

A concise chemoenzymatic total synthesis of neutral Globo-series glycosphingolipids Globo A and Globo B, and Forssman and para-Forssman antigens
http://link.springer.com/10.1007/s10719-023-10133-8
#Glycotime #Glycoconjugate

Konjac glucomannan attenuate high-fat diet-fed obesity through enhancing β-adrenergic-mediated thermogenesis in inguinal white adipose tissue in mice
http://link.springer.com/10.1007/s10719-023-10131-w
#Glycotime #Glycoconjugate

Differential analysis of core-fucosylated glycoproteomics enabled by single-step truncation of N-glycans
http://link.springer.com/10.1007/s10719-023-10130-x
#Glycotime #Glycoconjugate

Konjac glucomannan attenuate high-fat diet-fed obesity through enhancing β-adrenergic-mediated thermogenesis in inguinal white adipose tissue in mice
http://rd.springer.com/10.1007/s10719-023-10131-w
#Glycotime #Glycoconjugate

Galectin-12 modulates Kupffer cell polarization to alter the progression of non-alcoholic fatty liver disease
https://academic.oup.com/glycob/advance-article/doi/10.1093/glycob/cwad062/7233047?rss=1
#Glycotime #Glycobiology

Genetic and functional diversity of beta-N-acetylgalactosamine residue-targeting glycosidases expanded by deep-sea metagenome

#Glycotime #StructuralBiology @strucbio #Crystallography #Science
http://biorxiv.org/cgi/content/short/2023.07.28.550916v1?rss=1

A photoaffinity glycan labeling approach to investigate immunoglobulin glycan binding partners
https://academic.oup.com/glycob/advance-article/doi/10.1093/glycob/cwad055/7232176?rss=1
#Glycotime #Glycobiology

GlycoDraw: a python implementation for generating high-quality glycan figures
https://academic.oup.com/glycob/advance-article/doi/10.1093/glycob/cwad063/7232175?rss=1
#Glycotime #Glycobiology

Identification of potential classes of glycoligands mediating dynamic endothelial adhesion of human tumor cells
https://academic.oup.com/glycob/advance-article/doi/10.1093/glycob/cwad061/7230074?rss=1
#Glycotime #Glycobiology

Damn. Hyperglycemia (e.g. from diabetes) impacts DNA methylation levels by modifying the main DNA de novo methyltransferase's activity pattern.

"We report here that DNMT1 function is regulated by O-GlcNAcylation, a protein modification that is sensitive to glucose levels, and that elevated O-GlcNAcylation of DNMT1 from high glucose environment leads to alterations to the epigenome."

https://elifesciences.org/articles/85595

#epigenetics #Glycotime #diabetes

RT @: For those interested in what I'm up to, please find some information below.
TLDR: I have started a glycoscience company aiming to accelerate glycoscience research.Hello Glyco World.
We are a new #glycotime company with the central aim of accelerating glycoscience research.
We intend to do this in three ways:
- consulting
- analytical services
- glyco standard manufacturing

Find out more here:
https://proteaglyco.com/

Recognition factors of Dolichos biflorus agglutinin (DBA) and their accommodation sites
http://rd.springer.com/10.1007/s10719-023-10118-7
#Glycotime #Glycoconjugate

Mass photometry: A powerful tool for carbohydrates-proteins conjugation monitoring and glycoconjugates molecular mass determination
http://rd.springer.com/10.1007/s10719-023-10126-7
#Glycotime #Glycoconjugate

Unravelling the genetic causality of immunoglobulin G N-glycans in ischemic stroke
http://rd.springer.com/10.1007/s10719-023-10127-6
#Glycotime #Glycoconjugate

The generation of 5-N-glycolylneuraminic acid as a consequence of high levels of reactive oxygen species
http://rd.springer.com/10.1007/s10719-023-10121-y
#Glycotime #Glycoconjugate

Mucin glycans and their degradation by gut microbiota
http://rd.springer.com/10.1007/s10719-023-10124-9
#Glycotime #Glycoconjugate

Straightforward synthesis of the hexasaccharide repeating unit of the O-specific polysaccharide of Salmonella arizonae O62
http://rd.springer.com/10.1007/s10719-023-10122-x
#Glycotime #Glycoconjugate

Interactions between polysialic acid and dopamine-lead compounds as revealed by biochemical and in silico docking simulation analyses
http://rd.springer.com/10.1007/s10719-023-10119-6
#Glycotime #Glycoconjugate