Stephen Matheson🌵🌲 · @sfmatheson
714 followers · 726 posts · Server fediscience.org

so, systematically identified conserved, spatially organized anti-tumor immune hubs in solid tumors, associated with response

many other gene programs still to be explored in anti-tumor hubs
also other hubs such as an hub

now characterizing hubs using MERFISH

next steps to build mouse and organoid models to perturb hubs systematically

2/2

#inflammatory #Immunotherapy

Last updated 1 year ago

Noodlemaz · @noodlemaz
406 followers · 3046 posts · Server med-mastodon.com

We're about to move house but I bought a book about (bc I'm writing/talking about it a lot so I should know what I'm on about really)
Oops?

#Science #Immunotherapy #bookstodon

Last updated 1 year ago

Noodlemaz · @noodlemaz
397 followers · 2767 posts · Server med-mastodon.com

@haritulsidas So, going to the university site and the actual paper nature.com/articles/s41388-022

- what this is is a drug screen. In cells in the lab (in vitro), not in people (some mouse experiments). Also, it's specific to one of the >6 types of (TNBC), not BC or generally.

Interesting, and a good start, but it's not a 'breakthrough' as such. Drug screens return promising hits all the time!

(the part is super interesting too).

#cancer #breastcancer #cancerresearch #Immunotherapy

Last updated 1 year ago

Alan Kotok · @technewslit
1014 followers · 541 posts · Server journa.host
Alan Kotok · @technewslit
990 followers · 508 posts · Server journa.host
Alan Kotok · @technewslit
982 followers · 501 posts · Server journa.host

Trial Underway Testing Engineered Cancer-Killing Viruses

A clinical trial, testing stem cells for neurons fortified with tumor-killing viruses, administered its first doses to a patient with glioma, an aggressive type of brain cancer.

sciencebusiness.technewslit.co

#News #press #science #business #cancer #ClinicalTrial #gliomas #glioblastoma #BrainTumor #biotechnology #adenovirus #Immunotherapy #onoclytic #neurons #stemcells #grantfunding

Last updated 1 year ago

halama_immuno · @halama_immuno
329 followers · 1722 posts · Server mstdn.science
Gabriele Pollara · @gpollara
915 followers · 2801 posts · Server med-mastodon.com
halama_immuno · @halama_immuno
318 followers · 1685 posts · Server mstdn.science

The Helmholtz Institute for Translational Oncology -TRON is looking for a) a motivated master student for the establishment of a novel technology to identify reactive T cells and b) a motivated intern (8 weeks) to broaden the technology of gene delivery. Please contact through the website hi-tron.dkfz.de/

#hi #Immunotherapy #immunology #tcellbiology #oncology

Last updated 1 year ago

halama_immuno · @halama_immuno
306 followers · 1662 posts · Server mstdn.science

Groundbreaking ceremony for the new building of the Helmholtz Institute for Translational Oncology -TRON in Mainz (Germany), providing a space for novel cutting-edge development, and as tools in @mainz_de @unimainz @helmholtz @hereon @dkfz
dkfz.de/de/presse/pressemittei

#hi #Immunotherapy #personalizedmedicines #mRNAs #cancer #research

Last updated 1 year ago

David Basanta Gutierrez · @david
227 followers · 346 posts · Server fediscience.org

and explained by Kurzgesagt: youtu.be/uoJwt9l-XhQ

Video created with the help of my colleague Kim Luddy

#MoffittCancerCenter #Immunotherapy #immunoediting

Last updated 1 year ago

halama_immuno · @halama_immuno
293 followers · 1523 posts · Server mstdn.science

is a deadly disease. New data shows early benefits for addition of a personalized to after resection of the tumor. This feature in Deutsche Welle discusses the implications with Nina Bhardwaj and Drew Weissman t.co/j81AOXjcJS

#pancreaticcancer #Trial #mrna #vaccine #adjuvantchemotherapy #Immunotherapy #oncology

Last updated 1 year ago

halama_immuno · @halama_immuno
290 followers · 1475 posts · Server mstdn.science

Rare treated with : new data for subtype angiosarcoma, treated with double and showing clinical effects. But we still need better for in ... @chfloudas @cyrilpedia
jitc.bmj.com/content/9/8/e0029

#cancer #Immunotherapy #sarcoma #checkpointinhibitors #biomarkers #precisionmedicine #immunology

Last updated 1 year ago

halama_immuno · @halama_immuno
290 followers · 1475 posts · Server mstdn.science

@statto The approach is being investigated in other solid like or as well: reduce tumor burden with surgical resection and then add vaccination to the adjuvant (maximum) treatment...ideally a blueprint for success. Let's see what the trials will show...

#cancers #melanoma #colorectalcancer #immunology #Immunotherapy

Last updated 1 year ago

halama_immuno · @halama_immuno
290 followers · 1475 posts · Server mstdn.science
Alan Kotok · @technewslit
865 followers · 397 posts · Server journa.host

Precision T-Cell Solid Tumor Therapy Trial Underway

A clinical trial has begun testing a treatment for solid using engineered T-cells with proteins to attack specific tumor cells, but also avoid healthy cells.

sciencebusiness.technewslit.co

#tumor #cancers #News #science #business #ClinicalTrial #biotechnology #Tcells #Immunotherapy #solidtumor #precisionmedicine #companiondiagnostic

Last updated 1 year ago

Alan Kotok · @technewslit
858 followers · 390 posts · Server journa.host
halama_immuno · @halama_immuno
265 followers · 1189 posts · Server mstdn.science

Fantastic opening presentation by Samra Turaljic @thecrick@bird.makeup @thecrick on and molecular landscapes in and at the meeting in Mainz, Germany -TRON

#immunological #melanoma #renalcellcarcinoma #cimt2023 #hi #immunology #Immunotherapy

Last updated 1 year ago

Sean Gibbons · @gibbological
213 followers · 517 posts · Server mstdn.science

RT @cellhostmicrobe
Fuso induces tumor resistance to . New work reports that Fusobacterium nucleatum-derived succinic acid diminishes sensitivity to anti-PD-1 mAb in by impairing CD8+ -mediated antitumor immunity cell.com/cell-host-microbe/ful

#Immunotherapy #colorectalcancer #Tcell

Last updated 1 year ago

Patrick Mitchell · @psmitchej
113 followers · 73 posts · Server fediscience.org

RT @roose_jeroen
Last call - abstracts!!! @FaseB. Shaping up to be a great conference, judging from registrations that are in. . Great for trainees: travel grants! @barton_lab
@DanBStetson1 @griffiths_lab @RauchLab
@LabDac @MaxKrummel. Please RT. twitter.com/FASEBorg/status/16

#networking #Immunotherapy #immunology #signaling

Last updated 1 year ago