TrangAston :verified: · @CastlTrAstonDrs
1181 followers · 1967 posts · Server med-mastodon.com
#oncologresearch #cancerbiology @Nature The #KRAS crowd targets its next cancer mutations. Clinic-ready inhibitors, degraders and molecular glues are pushing cancer frontiers by targeting KRAS variants including KRAS-G12D.
📌 https://www.nature.com/articles/d41573-023-00015-x.pdf
📌 https://www.nature.com/articles/d41573-019-00195-5.pdf
📌 https://www.cancer.gov/research/key-initiatives/ras
#oncologresearch #cancerbiology #KRAS
@STAkrog · @STAkrog
8 followers · 413 posts · Server mstdn.socialV Postojni pripravili prvo borzo turističnih ponudnikov https://krog.sta.si/3138464 #turizem #borza #razvoj #kras
ashish(@tp53) · @acgt01
42 followers · 1410 posts · Server genomic.social
RT @norbertkraut1@twitter.com
The KRAS crowd targets its next cancer mutations https://www.nature.com/articles/d41573-023-00015-x
Insightful piece by @AsherMullard@twitter.com on drugging #KRAS beyond G12C mutants in @NatRevDrugDisc@twitter.com #KRASG12D #panKRAS inhibitors, molecular glues, degraders and more to come.
🐦🔗: https://twitter.com/norbertkraut1/status/1617624931545808897
Benedikt Mandl · @mandl
115 followers · 206 posts · Server mstdn.scienceRT @norbertkraut1
The KRAS crowd targets its next cancer mutations https://www.nature.com/articles/d41573-023-00015-x
Insightful piece by @AsherMullard on drugging #KRAS beyond G12C mutants in @NatRevDrugDisc #KRASG12D #panKRAS inhibitors, molecular glues, degraders and more to come.
Filip Janku · @CancerDoc
54 followers · 32 posts · Server med-mastodon.com
I am excited to see this paper coming up. Signals of activity noted with mono therapy and combination with cetuximab #KRAS #G12C #ColorectalCancer #TargetedTherapy #adagrasib
#KRAS #g12c #colorectalcancer #TargetedTherapy #adagrasib
Filip Janku · @CancerDoc
54 followers · 31 posts · Server med-mastodon.comI am excited to see this paper coming up. Signals of activity noted with mono therapy and combination with cetuximab #KRAS #G12C #ColorectalCancer #TargetedTherapy #adagrasib
#KRAS #g12c #colorectalcancer #TargetedTherapy #adagrasib
Rio Sugimura · @rio_sugimura
145 followers · 445 posts · Server med-mastodon.com
RT @StephenVLiu@twitter.com
Preclinical report of #KRAS G12D inhibitor MRTX1133 @CD_AACR@twitter.com. Efficacy noted in pancreatic models and interesting effect on the tumor microenvironment with this agent. Important target in NSCLC as well and this mutation often occurs in non-smokers.
🐦🔗: https://twitter.com/StephenVLiu/status/1604114196903313409
Wafik S. El-Deiry, MD PhD FACP · @weldeiry
96 followers · 187 posts · Server med-mastodon.com
Data presented by @tajiknia #AACRJCA22 shows MRTX1133 suppression of pERK at nM doses & synergies with 5-FU in CRC & pancreatic cancer cells with #KRAS G12D, G12V, & G13D. More studies needed before excluding non-G12D mutations from trials @BrownUCancer @BrownMedicine #eldeirylab
Josh Goldstein · @JoshGoldstein523
38 followers · 20 posts · Server med-mastodon.com
Project Livin’ Label: Sotorasib
Nicole Drezner of the FDA Oncology Center of Excellence leads a discussion of the development of sotorasib, an inhibitor that targets the KRAS G12C mutant, for adult patients with locally advanced or metastatic non-small cell #lungcancer. CME credit available: https://bit.ly/3iMJfKE #FDA #oncology #cme #cancerresearch #FDAapproval #kras
#lungcancer #FDA #oncology #CME #cancerresearch #fdaapproval #KRAS
KAP Jasa - kite team Slovenia · @kap_jasa
33 followers · 20 posts · Server mastodon.socialA long kite aerial archaeology story - a lost church found, a landscape palimpsest decyphered:
https://kapjasa.si/en/a-landscape-palimpsest-and-a-lost-church/
#kiteaerialphotography #kite #flying #aerial #KAP #archaeology #history #Karst #Kras #church #nearinfrared #NIR #NDVI #Gorjansko #Margareta #LIDAR #Slovenia
#kiteaerialphotography #kite #flying #aerial #kap #archaeology #history #karst #KRAS #church #nearinfrared #NIR #ndvi #gorjansko #Margareta #lidar #slovenia
Gregory Riely · @RielyMD
2 followers · 2 posts · Server med-mastodon.comMy first post here on mastodon. I am a #sloankettering #thoracic #oncologist interested in #clinicaltrials #clinicalresearch #oncology #lcsm #lungcancer #thoracicpathology #egfr #kras #thymoma #thymiccarcinoma
#sloankettering #thoracic #oncologist #clinicaltrials #clinicalresearch #oncology #lcsm #lungcancer #thoracicpathology #egfr #KRAS #thymoma #thymiccarcinoma
KAP Jasa - kite team Slovenia · @kap_jasa
21 followers · 18 posts · Server mastodon.socialDebela griža #hillfort as seen from a kite. Check out the full story about this BronzeAge beauty in Slovenia
kapjasa.si/en/a-prehistoric-jewel-debela-griza-hillfort/
#kiteaerialphotography #KAP #kite #kiteflying #aerial #photography #prehistoric #settlement #BronzeAge #IronAge #history #archaeology #DebelaGriža #VolčjiGrad #kras #enclosure #hillfort #walls #karst #Ricoh #RicohGR #rokkaku #Rokker #Slovenia
#hillfort #kiteaerialphotography #kap #kite #kiteflying #aerial #photography #prehistoric #settlement #bronzeage #ironage #history #archaeology #debelagriza #volcjigrad #KRAS #enclosure #walls #karst #ricoh #ricohgr #rokkaku #rokker #slovenia
