CellBioNews · @cellbionews
72 followers · 1596 posts · Server scientificnetwork.de
CellBioNews · @cellbionews
53 followers · 1276 posts · Server scientificnetwork.de
Elisabeth Lodder · @eml314
41 followers · 145 posts · Server genomic.social

Our latest work is out now in @Circ_Gen! 🎉

❗️Genetic variants in are associated with dilated cardiomyopathy and supraventricular arrhythmias

Big big thanks to all co-authors! @_CarolinePham Karolina Andrzejczyck, @JurgensSean, @steven_lubitz, @patrick_ellinor, @Jael_Copier, @ArthurWilde5, @cbezzina1, @eml314 and others ✨
ahajournals.org/doi/abs/10.116

#tnni3k #dcm #arrhythmia #genetics #Kinase #cardiology

Last updated 1 year ago

CellBioNews · @cellbionews
48 followers · 1057 posts · Server scientificnetwork.de
CellBioNews · @cellbionews
38 followers · 919 posts · Server scientificnetwork.de
CellBioNews · @cellbionews
38 followers · 872 posts · Server scientificnetwork.de
CellBioNews · @cellbionews
29 followers · 599 posts · Server scientificnetwork.de
The EMBO Journal · @embojournal
406 followers · 90 posts · Server sciencemastodon.com

What is the role of in the cellular response to stress?

Benjamin Chen at UT Southwestern, Hsinyu Lee at National Taiwan University, and coworkers implicate it as part of a that modulates --mediated ADP-ATP exchange over membranes to limit -derived ROS

embopress.org/doi/10.15252/emb

#dnadamage #Kinase #dnapkcs #oxidative #checkpoint #ant2 #vdac2 #mitochondrial #oxphos

Last updated 2 years ago

The EMBO Journal · @embojournal
361 followers · 54 posts · Server sciencemastodon.com

and synergize to induce cancer-related in
Clara Taffoni, Johanna Marines, Nadine Laguette et al at IGH Montpellier
embopress.org/doi/10.15252/emb

#dnadamage #DNARepair #Kinase #dnapk #cgas #inflammation #glioblastoma

Last updated 2 years ago

Alexis Verger · @AVerger
994 followers · 129 posts · Server fediscience.org

The code for the crystal structure of the active form of the MAP ERK2 is 2ERK 😬

rcsb.org/structure/2ERK

#Kinase #pdb #StructuralBiology #FunFact

Last updated 2 years ago

Dheeraj Prakaash · @dheerajprakaash
14 followers · 21 posts · Server mstdn.science

My latest paper published in
nature.com/articles/s41598-022-25603-6

of Src family Tyr Lck in a environment: Full-length dynamics, interactions, conformational change.

Study highlights: twitter.com/DJ_Biophys/status/1525101069332021248

#compchem #ScientificReports #moleculardynamics #simulation #Kinase #Tcell #membrane #protein #lipid

Last updated 2 years ago

Joseph P. · @tonic
229 followers · 118 posts · Server mstdn.science

Internally, adenosine is transformed into inosine and S-(5′-Adenosyl)-L-homocysteine (AdoHcy) by adenosine deaminase (ADA) and S-adenosyl-L-homocysteine hydrolase (SAHH) respectively. Additionally, adenosine helps to maintain the concentration of adenine /#nucleotides by converting adenosine into adenosine monophosphate. Finally, during cellular injury or hypoxia/#ischemia, adenosine is formed from and is transported inside the using proteins.

#Kinase #nucleosides #atp #cell #transmembrane

Last updated 2 years ago

CellBioNews · @cellbionews
4 followers · 19 posts · Server scientificnetwork.de

Researchers find repeated duplications and genetic diversification in protein R in mouse-eared .

phys.org/news/2022-11-gene-dup

#gene #Kinase #bats #PKR #EIF2AK2 #phylogenetics

Last updated 2 years ago

Alexander Jais 🍟🧠 · @alexjais
10 followers · 8 posts · Server fediscience.org

RT @MolMetab@twitter.com

This paper by Anna Juliane Vesting et al. shows that -specific loss of the NFκB-inducing (NIK) improved complications and reduced .

👩‍🔬👨‍🔬@MPI_Metabolism@twitter.com @UniCologne@twitter.com @HIMAG_Leipzig@twitter.com
➡️sciencedirect.com/science/arti

🐦🔗: twitter.com/MolMetab/status/15

#hepatocarcinogenesis #nash #metabolic #Kinase #hepatocyte

Last updated 2 years ago

Marco Radi · @marcoradi
116 followers · 46 posts · Server qoto.org
Alexis Verger · @AVerger
815 followers · 83 posts · Server fediscience.org

Amazing work showing that of the module (CDK) of Mediator complex in chimeric receptor T cell (CAR T) resulted in enhanced effector function and increased activity (disruption of CDK module increases core Mediator occupancy at )

science.org/doi/10.1126/scienc

#enhancers #chromatin #Antitumor #antigen #Kinase #disruption #genetic #paperoftheday

Last updated 2 years ago

TrangAston :verified: · @CastlTrAstonDrs
251 followers · 210 posts · Server med-mastodon.com
Dave Briggs :protein: · @xtaldave
560 followers · 507 posts · Server xtaldave.net

I'd better do another now I've moved my home.

Hi, I'm Dave. I'm a Principal Laboratory (aka. Scientific officer) at the Francis Crick Insititute in .

I'm a by training. I help run a group that studies in human and .

I do and .

#Science #Glycobiology #DrugDesign #Biophysics #cryoem #crystallography #disease #health #signaling #Kinase #StructuralBiologist #London #scientist #research #fediverse #introduction

Last updated 2 years ago