#Viralimmunology #pedsICU The findings underscore the potential of inflammatory cytokine signaling, like IL-6, during acute viral infections to induce enduring epigenetic changes in HSPC and progeny innate immune cells ,potentially influencing various post-infection phenomena in humans, including tissue repair, protection against other infections, chronic inflammation, & long-term sequelae in #Postcovid , #LongCovid & #LongCovidKid

#Viralimmunology #LongCovidKid understanding the Immune responses to #SARSCoV2 infection & vaccination in children
#PostCovid in adults associated with #viralpersistence in 🩸& MIS-C in children is associated with viral persistence in the intestine which is suggesting that tissue specific differences or age-associated differences in immune responses to persistent #SARSCoV2 🦠 may explain these different presentations.
https://www.sciencedirect.com/science/article/pii/S1044532323000854#fig0010

#IDMastodon #PedsID Details on the pathogenesis, clinical presentation, and treatment for #postCOVID conditions in children are beyond the scope of these Guidelines. @CDCgov provides additional information about the incidence, presentation, and management strategies for #LongCovidKid as well as adults. @nih

Whether these events can also occur with new variants of #SarsCoV2 or in previously vaccinated children is still unknown.Although the biological significance of the possibility for viral spread and persistence in children is unknown, the substantial evidence for it should not be neglected, & should inform future clinical, biological, and pharmacological studies.
Viral persistence in #LongCovidkid @LancetMicrobe
https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(23)00115-5/fulltext

👉"Nous avons un tsunami de handicaps à des degrés divers chez + de 70 000 enfants actuellement au Royaume-Uni"

Sammie McFarland de @LongCovidKids évoque sur ITV News Meridian. les difficultés du #CovidLongPediatrique.

📌Pour regarder l'émission / to watch this TV program : https://www.youtube.com/watch?v=y4I2TgHrvlg

#ApresJ20 #LongCovid #LongCovidKid #CovidLong #CovidLongPediatrique

💥Nous arrivons au dernier jour du LongCovidAwarenessMonth💥

🎯Ensemble, continuons d’alerter, de sensibiliser, d’informer au quotidien sur le #CovidLong.

🔴Rendez-vous le 15 avril à 15h pour poster avec le hashtag #LongCovidAwareness!

#ApresJ20 #LongCovid #LongCovidKid
#CovidLong #LongCovidAwarenessDay #LongCovidAwarenessMonth

LCK champion Dr Binita Kane spoke to @itvmeridian about Long Covid, service provision and the need for paediatric biomedical research. / investment for @NHSEngland

#LongCovidKid #LongCovid #ITV

https://www.itv.com/news/meridian/2023-03-30/nhs-doctor-takes-housebound-daughter-to-germany-for-long-covid-treatment

📢📢📢La journaliste Stacey Poole d'@ITV Meridian publie une série sur le #CovidLong pédiatrique qui DEVASTE la vie de ces enfants & adolescents!

💔Les mots d'Emily et Hannah sont à écouter💔

"C'était juste incontrôlable -je n'avais jamais ressenti ce genre de douleur auparavant"

"Cela ne se ressent toujours plus comme mon corps.
Ce n'est tout simplement pas moi" témoigne Hannah.

https://www.itv.com/news/meridian/2023-03-26/my-world-came-crashing-down-teen-describes-her-long-covid-battle?fbclid=IwAR125op47Pa__ljH1ArCmAjsAbc6xa6TjRHPPxZq9CT1qlcKcmPyCig1_Nc

#ApresJ20 #LongCovid #CovidLong #LongCovidKid #LongCovidAwarenessMonth

#IDMastodon #neuroimmunology #LongCovid #LongCovidKid Incidence of #epilepsy and #seizures Over the First 6 Months After a #COVID19 Diagnosis
📌 https://n.neurology.org/content/100/8/e790
📌 https://n.neurology.org/search/Covid19?facet%5Bpublication-date%5D%5B0%5D=2023

#IDMastodon #PedsICU @WHO @resiapretorius Excellent Information for clinicians on #LongCovidKid A clinical case definition for #postCOVID19 condition in children and adolescents by expert consensus, 16 February 2023
📌 https://apps.who.int/iris/rest/bitstreams/1491580/retrieve
📌 https://www.who.int/publications/i/item/WHO-2019-nCoV-Post-COVID-19-condition-CA-Clinical-case-definition-2023-1

@aaas Recap 2022 the complexities facets of #COVID19 , #LongCovidKid & children
https://www.science.org/doi/10.1126/science.ade1675

#PedsICU #PedsCardiology Mid/Long-Term AV Functional Changes in Children after Recovery from #COVID19 / #LongCovidKid .The persistence of LV myocardial defor- mation abnormalities after an average follow-up of 148 ± 68 days asymptomatic or mildly symptomatic infection course (WHO stages 0 or 1) in healthy chil- dren. Myocardial alterations were more pronounced during 2nd wave of #COVID19.
📌 https://mdpi-res.com/d_attachment/jcm/jcm-12-00186/article_deploy/jcm-12-00186-v2.pdf?version=1672282010

If like
@MichelZumkeller 🇫🇷,
@LCNMUK 🇬🇧,
@melanieddr 🇫🇷,
@ChiaraAlfieri10 🇮🇹,
@dgurdasani1 🇬🇧,
@preshitorian 🇬🇧
you too want to sign our Open Letter to call
@EmmanuelMacron
to act on #LongCovid #LongCovidKid!🔥
👉https://tinyurl.com/3tu452vx!

#CovidLong #ApresJ20