Ecited to share our work on how ECF #transporters use ATP binding to charge a molecular spring and tune the #membrane shape to expel membrane-embedded substrate-binding proteins from the docking site into the membrane. #cryoEM #Biochemistry #MDsimulations https://rdcu.be/dhJvy
#transporters #membrane #cryoem #biochemistry #MDsimulations
RT @MPIbp
Forming cup-shaped membranes, the cell builds autophagosomes that digest cellular waste. By studying interactions of regulatory proteins with these highly curved membranes via #MDsimulations, scientists from our @HummerLab contributed to new insights into autophagosome formation.