David Heppner · @heppnerd
79 followers · 39 posts · Server mstdn.science

New ChemRxiv preprint! “Pitfalls and considerations in determining the potency and mutant selectivity of covalent inhibitors.” Collaboration between our group and AssayQuant Technologies, Inc. chemrxiv.org/engage/chemrxiv/a

#egfr #MedicinalChemistry #oncology

Last updated 1 year ago

Beilstein-Institut · @BeilsteinInstitut
266 followers · 14 posts · Server hessen.social

You are cordially invited to submit your latest research to the thematic issue “Modern ” edited by Huan-Ming Huang from ShanghaiTech University 🇨🇳 in the 💎🔓 Beilstein Journal of Organic Chemistry.

🔗 beilstein-journals.org/bjoc/se

#radicalchemistry #bjoc #electrosynthesis #photoredoxchemistry #MedicinalChemistry #materialscience

Last updated 1 year ago

Aled · @aledmedwards
31 followers · 277 posts · Server mstdn.science

RT @School_Pharmacy
We're looking for a highly motivated in to join our team and contribute to our research projects in .

The deadline for applications is 16 April. To find out more and to apply, visit: bit.ly/3ZCQEMA @MatToddChem

#researchfellow #proteinscience #MedicinalChemistry

Last updated 2 years ago

Miranda Lynch · @MirandaLynchPhD
287 followers · 222 posts · Server mathstodon.xyz

@heppnerd Congrats on the new role, Dave! Nicely done.

#MedicinalChemistry

Last updated 2 years ago

Chris Swain · @macinchem
86 followers · 97 posts · Server sciencemastodon.com
Marco Radi · @marcoradi
164 followers · 121 posts · Server qoto.org

NPP-669 is a promising acting as agent () against multiple DNA .
An excellent example on how / play a key role in the improvement of and clinical efficacy of candidates.

pubs.acs.org/doi/full/10.1021/

#Cidofovir #prodrug #broad #spectrum #BSAA #antiviral #viruses #chemistry #MedicinalChemistry #drug #bioavalilability

Last updated 2 years ago

Sam Levine · @SRLevine
85 followers · 251 posts · Server urbanists.social

Announcement I've been sitting on: I'm joining UCI's new Institute for Neurotherapeutics! While Rob Spitale (@SpitaleLab@twitter.com) is affiliated with the INT he is on leave from the university (hence my job change) and I'll be working for Brian Paegel (@BrianDNA@twitter.com) and INT director Al La Spada.

news.uci.edu/2022/10/18/uci-la

#uci #neurotherapeutics #chemistry #chemicalbiology #chembio #chemiverse #medchem #MedicinalChemistry #drugdiscovery #collaboration #Science

Last updated 2 years ago

opnMe · @opnMe
2 followers · 5 posts · Server techhub.social

Hi All, new on Mastodon, I am happy to share our website opnMe.com which support for free academic scientists with high quality tool compounds free of charge. Visit us. opnMe is the open innovation website of Boehringer Ingelheim
Florian

#MedicinalChemistry

Last updated 2 years ago

Chembellenie · @Chembellenie
106 followers · 63 posts · Server scicomm.xyz

Viva 3 ✔️

Congratulations to the new Dr. Will on completing his PhD viva. Will’s project was on the design, synthesis and testing of libraries of protein degraders, and he is now putting his training in and into good use in his new job at GSK. That’s all for - but we don’t have long to wait before the next one - Dani’s transfer viva in two weeks time!

Always sad to say goodbye but great to celebrate our students progressing!

#phd #ThreeVivaFortnight #TPD #MedicinalChemistry

Last updated 2 years ago

Chembellenie · @Chembellenie
102 followers · 46 posts · Server scicomm.xyz

Viva 2 ✅ Congratulations Katie on completing transfer viva for formal registration as a PhD student. Katie’s project is on designing, making and testing monovalent degraders, working across our chemistry and biology teams in the (Centre for Cancer Drug Discovery) at ICR.

#chemistry #MedicinalChemistry #TPD #CCDD

Last updated 2 years ago

Marco Radi · @marcoradi
65 followers · 20 posts · Server qoto.org

-Time for a short -

I am a group leader in at the University of Parma. My lab combines & techniques to develop novel pharmacological tools to study different Chronic Diseases (, , , , ) and Infective Agents (, , , , ).
We are particularly interested in the development of inhibitors and open to new in .
(sooner or later) about the and

#chemical #computational #cysticfibrosis #Hypercholesterolemia #alzheimer #cancer #SarsCoV2 #enterovirus #Flavivirus #monkeypox #hiv #introduction #MedicinalChemistry #ibd #MultiTarget #collaborations #drugdiscovery #tooting #chemistry #science

Last updated 2 years ago

Chembellenie · @Chembellenie
102 followers · 46 posts · Server scicomm.xyz

It’s a Three Viva Fortnight in our team!

One down …
Viva 1: Charlie (PhD) today ✅

And two to go …
Viva 2: Katie (transfer to PhD) on Thursday
Viva 3: Will (PhD) next Thursday

Congratulations to the new Dr. Charlie!
Great to see talented scientists ticking off another milestone, and a relief to see that the first project proposal I was responsible for writing didn’t end in disaster…!

Thanks to the examiners for giving up their time and effort!

#celebrate #ICR #MedicinalChemistry #phd

Last updated 2 years ago

Chembellenie · @Chembellenie
102 followers · 46 posts · Server scicomm.xyz

Some nice work from Ethan Toriki, James Papatzimas, Daniel Nomura and coauthors on bioRxiv biorxiv.org/content/10.1101/20

I think this is the first example in the “glue degraders” field where someone found a “degrading handle” that could be attached to multiple different inhibitors to give degradation of different proteins. A nice step forward in the rational design of molecular glue degraders!

#degraders #MedicinalChemistry #TPD

Last updated 2 years ago

Chembellenie · @Chembellenie
102 followers · 46 posts · Server scicomm.xyz

I will try and use this account to
- share some nice science (from us and other
- ask and answer questions about research
- explain some key concepts about my work (good practice!)

Always happy to hear from people who want to know more, or who are interested in careers in or

I’m on this Sci Comm server because I like to try to explain things to people with different backgrounds, but that doesn’t mean I’m good at it, so bear with me!

#drugdiscovery #MedicinalChemistry #scicomm

Last updated 2 years ago

Chembellenie · @Chembellenie
102 followers · 46 posts · Server scicomm.xyz

I’m a researcher in - I design and make chemicals towards medicinal application at the Institute of .

One focus is on - targeted protein degradation, a relatively new area, where we aim to find molecules that dont just block the function of a protein, but wipe it out completely.

I believe sharing knowledge is absolutely critical to science (Here’s me trying some at Pint of Science 2022!) - so ask me anything about !

#drugdiscovery #scicomm #TPD #cancerresearch #MedicinalChemistry

Last updated 2 years ago

Dave Briggs :protein: · @xtaldave
692 followers · 913 posts · Server xtaldave.net
Cedric Graebin · @cedric
88 followers · 88 posts · Server fediscience.org

Hi there! My name is Cedric and I'm a synthetic medicinal chemist. I design and develop new molecules hoping to find something useful to treat neglected tropical diseases such as , and disease.

Currently I am a trainer at the Wellcome Centre for Anti-Infectives Research at the University of Dundee, Scotland. My interests are , , and some on the side.

#python #compchem #drugdesign #chemistry #MedicinalChemistry #Chagas #Leishmaniasis #malaria #introduction

Last updated 2 years ago