Javier Díaz-Nido · @Javier_DN
170 followers · 351 posts · Server red.niboe.infoMultifaceted nanoparticles: emerging mechanisms and therapies in neurodegenerative diseases.
Friedreich’s ataxia represents a test case to validate the potential of therapeutic strategies based on nanoparticles.
#Neuroscience #Brain #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Cerebellum #Ataxia #FriedreichAtaxia #HereditaryAtaxias #Ataxias #NeurogeneticDiseases #Neurogenetics
#Genetics #HereditaryDiseases #GeneticDiseases
#ClinicalTrial
#GeneTherapy
#Neuroinflammation
#Mitochondria #MitochondrialDysfunction
#Nanoparticles #Nanomedicine #Nanobiotechnology
#Biomedicine #Health
https://academic.oup.com/brain/article/doi/10.1093/brain/awad014/7024724
#health #biomedicine #Nanobiotechnology #Nanomedicine #nanoparticles #MitochondrialDysfunction #mitochondria #neuroinflammation #genetherapy #ClinicalTrial #GeneticDiseases #HereditaryDiseases #genetics #neurogenetics #NeurogeneticDiseases #Ataxias #HereditaryAtaxias #FriedreichAtaxia #ataxia #Cerebellum #Neurodegeneration #NeurodegenerativeDiseases #NeurologicalDiseases #brain #neuroscience
Javier Díaz-Nido · @Javier_DN
170 followers · 349 posts · Server red.niboe.infoAPOE expression and secretion are modulated by mitochondrial dysfunction
This study presents compelling evidence that ApoE is upregulated in various models of mitochondrial respiratory chain dysfunction. The work is of fundamental interest for those studying neurodegeneration and the role of ApoE in Alzheimer's disease; future work will be needed to reveal the molecular basis of this dramatic phenotype.
#Biomedicine #Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Alzheimer #ApoE #Neurogenetics #Mitochondria #MitochondrialDysfunction
#MitochondrialDysfunction #mitochondria #neurogenetics #ApoE #Alzheimer #Neurodegeneration #NeurodegenerativeDiseases #NeurologicalDiseases #neurology #brain #neuroscience #biomedicine
Philzilla℠ · @NotARealName
182 followers · 198 posts · Server mastodon.socialRejuvenating properties of light, controlling #MitochondrialDysfunction. Note to myself really, but I’m going to be extending my mornings’ #FarRed #LED eye bath as much as I can. If you’ve read this far you might be interested to know my eyes’ prescription improved significantly, after 6m of 5-15mins morning sessions, through closed eyelids, of ~25W 670nm point source (LED cob) @ 20cm distance. #Anecdotal #neuroscience #RetinalHealth https://www.nature.com/articles/s43587-022-00340-7
#MitochondrialDysfunction #farred #led #anecdotal #neuroscience #retinalhealth