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🟣#H2020 @caramba_project is evaluating the safety and efficacy of the revolutionary CAR-T cell technology to tackle #MultipleMyeloma, a rare hematologic disease

🐦🔗: https://n.respublicae.eu/EU_HaDEA/status/1630487295739543553

#H2020 #MultipleMyeloma

Last updated 1 year ago

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CavalliLab · @giacomocavalli

147 followers · 39 posts · Server mastodon.social

New discoveries about #Polycomb #EZH2 function in #MultipleMyeloma and a therapeutic avenue here:
Dissecting and targeting noncanonical functions of EZH2 in multiple myeloma via an EZH2 degrader. Oncogene (2023). https://doi.org/10.1038/s41388-023-02618-5

#polycomb #ezh2 #MultipleMyeloma

Last updated 1 year ago

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ArcticLlama · @arcticllama

23 followers · 674 posts · Server mastodon.social

Open media

Probably not a lot new since the one they just did in Asia, but it's virtual and the multiple myeloma presentation is at 9:00 am (Eastern) if you feel like listening to experts talk about what lurks in your body. #multiplemyeloma #myeloma
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RT @hemoncbp
GW 2023 Hematology Update Symposium is Sat, Feb, 25, 8AM EST. Join us Live In-Person or via Virtual Livestream https://bit.ly/hemaupdate2023

Register Today!
Sat, Feb 25, 8:00 AM EST
Mar…
https://twitter.com/hemoncbp/status/1625623520347582464

#MultipleMyeloma #myeloma

Last updated 1 year ago

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Mwinyele · @moringaottawa

28 followers · 76 posts · Server eldritch.cafe

@jetton for anyone else who finds themselves furrowing their brows at the word #cytogenetics ,
here’s a full (unsolicited) rundown from #sciencedirect :

What is cytogenetics?
Cytogenetics is the oldest and most basic technique used to perform #cytogenomic studies. It is far from being outdated and offers unique possibilities to approach the whole genome of a given species at once; cytogenetics takes advantage of the possibility of making a genome visible to the human eye under a microscopic lens (Liehr, 2020, 2021a, 2021b).
Cytogenetics is defined slightly differently, according to the following three references:
•
Cytogenetics is “the study of chromosomes, which are long strands of DNA and protein that contain most of the genetic information in a cell. Cytogenetics involves testing samples of tissue, blood, or bone marrow in a laboratory to look for changes in chromosomes, including broken, missing, rearranged, or extra chromosomes. Changes in certain chromosomes may be a sign of a #geneticdisease or condition or some types of #cancer . Cytogenetics may be used to help diagnose a disease or condition, plan treatment, or find out how well treatment is working” (Cytogenetics - #CancerDictionary 2020).
•
“Cytogenetics is essentially a branch of genetics but is also a part of #cellbiology /#cytology (a subdivision of #humananatomy ), that is concerned with how the chromosomes relate to #cellbehavior , particularly to their behavior during mitosis and meiosis. Techniques used include #karyotyping , analysis of G-banded chromosomes and other #cytogenetic banding techniques” (Cytogenetics - Wikipedia, 2020).
•
Cytogenetics is “the branch of #genetics that is concerned primarily in cellular components, especially chromosomes, in relation to #heredity , #geneticanomalies , and #pathologicconditions . It is the branch of genetics that deal at the cellular level” (Cytogenetics - #BiologyOnline , 2020).
Thus, cytogenetics, as discussed here, is about studying chromosomes by the classical methods outlined later. It is single-cell oriented, and studies chromosomes for research and #diagnostic purposes. In research, it provides basic information about genomes, including necessary insights into chromosome numbers, shape, and structures, like telomeres, centromeres, chromosome-arms, or banding pattern. In addition, it is of interest that mitotic as well as meiotic chromosomes can be accessed. Overall, cytogenetics is the “entry method,” in case genetic diagnostics is required in pre-, postnatal, or #leukemia diagnostics, but also in studies on #karyotypes and genomes in #evolutionresearch (#Liehr , 2020).
#cytogenecist #cytogeneticists #diagnostics #cellbehaviour #cancerresearch #oncologist #molecularhemopathology #oncology #MultipleMyeloma #genomemaps #geneticmapping #linkagemaps #cytogeneticmapping #rflp #vntr #meded #humanchromosomes

#cytogenetics #sciencedirect #cytogenomic #geneticdisease #cancer #cancerdictionary #cellbiology #humananatomy #cellbehavior #karyotyping #cytogenetic #genetics #heredity #geneticanomalies #pathologicconditions #biologyonline #diagnostic #leukemia #karyotypes #evolutionresearch #liehr #cytogenecist #cytogeneticists #diagnostics #cellbehaviour #cancerresearch #oncologist #molecularhemopathology #oncology #MultipleMyeloma #genomemaps #geneticmapping #linkagemaps #cytogeneticmapping #rflp #vntr #meded #humanchromosomes

Last updated 2 years ago

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Yan Leyfman, MD · @yleyfman

117 followers · 119 posts · Server med-mastodon.com

#oncology #immunology #immunotherapy #genetherapy #cancer #cancerawareness #cancerresearch #oncologist #oncología #oncologyresearch #clinicaltrial #clinicalresearch #oncology #immunology #immunotherapy #genetherapy #cancer #cancerawareness #cancerresearch #medicine #research #multiplemyeloma #myeloma #bloodcancer #hematologyoncology #hematologia #hematology

#oncology #immunology #Immunotherapy #genetherapy #cancer #cancerawareness #cancerresearch #oncologist #oncologia #oncologyresearch #clinicaltrial #clinicalresearch #medicine #research #MultipleMyeloma #myeloma #bloodcancer #hematologyoncology #hematologia #hematology

Last updated 2 years ago

Original post

terryflynn · @terryflynn

2 followers · 20 posts · Server mastodonapp.uk

Hey #GylesBrandreth doesn't cover himself in glory, giving details of #QueenElizabethII #cancer to sell a book, but now the cat is out of the bag, why give half baked explanation? #MultipleMyeloma https://www.theguardian.com/uk-news/2022/dec/30/the-day-queen-elizabeth-died-the-inside-story-of-her-final-hours

#gylesbrandreth #QueenElizabethII #cancer #MultipleMyeloma

Last updated 2 years ago

Original post

terryflynn · @terryflynn

2 followers · 19 posts · Server mastodonapp.uk

Hey #GylesBrandreth doesn't cover himself in glory, giving details of #QueenElizabethII #cancer to sell a book, but now the cat is out of the bag, why give half baked explanation? #MultipleMyeloma https://www.theguardian.com/uk-news/2022/dec/30/the-day-queen-elizabeth-died-the-inside-story-of-her-final-hours

#gylesbrandreth #QueenElizabethII #cancer #MultipleMyeloma

Last updated 2 years ago

Original post

Sigrid Skånland · @sigridskanland

10 followers · 3 posts · Server mstdn.social

Open media

Our last publication is online! We show that protein profiles, in addition to mutational status, of multiple myeloma cell lines predict drug sensitivity. Another step towards showing that functional tests are relevant in hematology.
Congratulations to #MariaserenaGiliberto for publishing her last PhD paper!
#multiplemyeloma #functionalprecisionmedicine
https://pubmed.ncbi.nlm.nih.gov/36523963/

#functionalprecisionmedicine #MultipleMyeloma #mariaserenagiliberto

Last updated 2 years ago

Original post

Sigrid Skånland · @sigridskanland

23 followers · 31 posts · Server mstdn.social

Open media

Our last publication is online! We show that protein profiles, in addition to mutational status, of multiple myeloma cell lines predict drug sensitivity. Another step towards showing that functional tests are relevant in hematology.
Congratulations to #MariaserenaGiliberto for publishing her last PhD paper!
#multiplemyeloma #functionalprecisionmedicine
https://pubmed.ncbi.nlm.nih.gov/36523963/

#functionalprecisionmedicine #MultipleMyeloma #mariaserenagiliberto

Last updated 2 years ago

Original post