Badwolf303 · @marcibadwolf303
617 followers · 6043 posts · Server mastodon.world
Heidi61 · @hjs1961
66 followers · 230 posts · Server mastodonapp.uk

Sharing on behalf of a colleague--
The is on a mission to find the next addition to our dynamic board of Trustees. Together, we'll make a real impact in the lives of young people with muscular dystrophy and allied neuromuscular conditions.
charityjob.co.uk/volunteer-job

#musclehelpfoundation #Trustee #MuscularDystrophy #neuromuscularconditions

Last updated 2 years ago

Dave Briggs :protein: · @xtaldave
1208 followers · 4053 posts · Server xtaldave.net

Dystroglycan / Muscular Dystrophy news:

N-terminal domain on dystroglycan enables LARGE1 to extend matriglycan on α-dystroglycan and prevents muscular dystrophy

elifesciences.org/articles/828

#MuscularDystrophy #Glycotime #Science #research

Last updated 2 years ago

Wolfgang Stein · @crablab
4 followers · 5 posts · Server mastodon.world
Dave Briggs :protein: · @xtaldave
1133 followers · 2886 posts · Server xtaldave.net

🚨 Preprint
Dystrophin is a mechanical tension modulator
biorxiv.org/cgi/content/short/

#MuscularDystrophy

Last updated 2 years ago

Dave Briggs :protein: · @xtaldave
1066 followers · 2518 posts · Server xtaldave.net

... today the paper describing the structure of the enzyme responsible for synthesising this this sugar polymer (LARGE1) was published, giving us more insight into how and why folks get muscular dystrophy, and maybe providing a route map to how we might ease their symptoms.

journals.plos.org/plosone/arti

#scicomm #MuscularDystrophy

Last updated 2 years ago

Francoise Helmbacher · @F_Helmbacher
314 followers · 108 posts · Server mstdn.social
Michaela Haas · @mihaas
4 followers · 3 posts · Server climatejustice.social

Hope for patients with : Read my latest on Leaps.org
leaps.org/muscular-dystrophy/p

#MuscularDystrophy

Last updated 2 years ago

Dave Briggs :protein: · @xtaldave
560 followers · 507 posts · Server xtaldave.net

The interaction between Laminin and Matriglycan is really important for muscle formation and stability, and patients who cannot synthesise Matriglycan develop .

You can read this paper describing this work here:
ncbi.nlm.nih.gov/pmc/articles/

Also, is and has been an discipline for many decades, and the structure I determined can be found :

rcsb.org/structure/5ik5

- or -

ebi.ac.uk/pdbe/entry/pdb/5ik5

#opendata #structuralbiology #openaccess #MuscularDystrophy

Last updated 2 years ago

Anubis2814 · @anubis2814
65 followers · 32020 posts · Server toot.cat

RT @GENbio@twitter.com

for a Rare Overcomes Earlier Roadblocks

A preclinical study provides proof-of-concept evidence for a new gene therapy approach that offers a potential long-term treatment for limb-girdle muscular dystrophy 2B. Read more: ow.ly/9PZY50HnAra

🐦🔗: twitter.com/GENbio/status/1479

#genetherapy #MuscularDystrophy

Last updated 3 years ago