https://twitter.com/maxberger/status/1632963498824040449?s=12&t=4ZT29WNe_iCR2VIiSTnoWA

#elon #MuscularDystrophy #douchebagbillionaires #twitter #fascists

Sharing on behalf of a colleague--
The #MuscleHelpFoundation is on a mission to find the next addition to our dynamic board of Trustees. Together, we'll make a real impact in the lives of young people with muscular dystrophy and allied neuromuscular conditions.
https://www.charityjob.co.uk/volunteer-jobs/muscle-help-foundation/trustees/880627 #Trustee #MuscularDystrophy #NeuromuscularConditions

Dystroglycan / Muscular Dystrophy news:

N-terminal domain on dystroglycan enables LARGE1 to extend matriglycan on α-dystroglycan and prevents muscular dystrophy

#MuscularDystrophy #GlycoTime #Science #Research

https://elifesciences.org/articles/82811?utm_source=feedly&utm_medium=webfeeds

Great news from the Engelke lab at Illinois state university.

https://news.illinoisstate.edu/2023/01/1-4-million-nih-grant-to-dr-martin-engelkes-cellular-studies/

#neuroscience #MuscularDystrophy

🚨 Preprint
Dystrophin is a mechanical tension modulator
http://biorxiv.org/cgi/content/short/2022.12.23.521750v1?rss=1

#MuscularDystrophy

... today the paper describing the structure of the enzyme responsible for synthesising this this sugar polymer (LARGE1) was published, giving us more insight into how and why folks get muscular dystrophy, and maybe providing a route map to how we might ease their symptoms.

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0278713

#SciComm #MuscularDystrophy

Because the search function here doesn't work so well, as I've seen others do, here is a list of hashtags # I'm following (some of which I'm also adding to my profile):

#DevBio
#DevBiol
#Development
#Myoverse (as a possible equivalent of #Myotwitter )
#Morphogenesis
#Regeneration #MuscularDystrophy
#FSHD
#Mechanobiology
#CellBiology
#Neurobiology
#NeuroDev
#Imaging
#biorxiv
#preLights
#Microscopy
#axonguidance

Hope for patients with #musculardystrophy: Read my latest on Leaps.org
https://leaps.org/muscular-dystrophy/particle-1

The interaction between Laminin and Matriglycan is really important for muscle formation and stability, and patients who cannot synthesise Matriglycan develop #MuscularDystrophy.

You can read this paper describing this work #OpenAccess here:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030134/

Also, #StructuralBiology is and has been an #OpenData discipline for many decades, and the structure I determined can be found :

https://www.rcsb.org/structure/5ik5

- or -

https://www.ebi.ac.uk/pdbe/entry/pdb/5ik5

RT @GENbio@twitter.com

#GeneTherapy for a Rare #MuscularDystrophy Overcomes Earlier Roadblocks

A preclinical study provides proof-of-concept evidence for a new gene therapy approach that offers a potential long-term treatment for limb-girdle muscular dystrophy 2B. Read more: http://ow.ly/9PZY50HnAra

🐦🔗: https://twitter.com/GENbio/status/1479874301390110726