Splendid #SciArt by Kristy Red-Horse lab

Endocardial Origin of Coronary #EndothelialCell +Arteriogenesis

A fascinating BMP2+ transitioning e17.5 coronary EC population

How EC & nonvascular BMPs coordinate heart #Angiogenesis😆

Exogenous BMP2 synergizes with VEGF-A⏫endocardial-derived Angiogenic sprouting from e10.5🫀ventricle explants

LDN193189, BMPR inhibitor,⏬endocardial contribution to coronary vascularization

AAV9-cTnt-Bmp2⏫endocardial-derived angiogenesis in neonatal #MyocardialInfarction🤠

Dev Cell 2022 @kristyredhorse
https://www.cell.com/developmental-cell/fulltext/S1534-5807(22)00759-6

Cell Encapsulator made as PLLA/PLGA (50:50) electrospun porous (750 nm) scaffold

⏫👤Cardiac mesenchymal cell survival (1 mo in vivo) & #Exosome secretion

Implanted locally->⏫🐭#Limbischemia & #MyocardialInfarction

Dr. David Lundy lab J Controlled Release 2022
https://www.sciencedirect.com/science/article/pii/S0168365922007350