“we identified a sparse subset of neurons in the primary visual cortex (V1) and higher visual areas that respond emergently to ICs [illusory contours]. We found that these highly selective "IC-encoders" mediate the neural representation of IC inference. Strikingly, selective activation of these neurons using two-photon holographic optogenetics was sufficient to recreate IC representation in the rest of the V1 network, in the absence of any visual stimulus.”

From: “Recurrent pattern completion drives the neocortical representation of sensory inference” by Shin et al. 2023 https://www.biorxiv.org/content/10.1101/2023.06.05.543698v1

#neuroscience #NeuroPixels #mouse

We developed a framework based on @zarr_dev to benchmark lossless and lossy compression of #Neuropixels and similar data. The benchmark datasets included NP1 and NP2 recordings, available on Registry of Open Data on
@AWS

https://registry.opendata.aws/allen-nd-ephys-compression/

(2/n)

Do you use #neuropixels or #highdensity probes? Are your recordings filling up your hard drives?
We got you covered!

In the first preprint from
@AllenInstitute
for Neural Dynamics, we looked at ways to reduce the footprint of #ephys data.

https://www.biorxiv.org/content/10.1101/2023.05.22.541700v2

(1/n)

@ArminLak

Wow, the #Neuropixels preprint just landed!

“Large-scale brain-wide neural recording in nonhuman primates” Trautmann et al. 2023

“4416 electrodes along a 45 mm shank, and 2496 along a 25 mm shank. … users can programmably select 384 channels, enabling simultaneous multi-area recording with a single probe. We demonstrate recording from over 3000 single neurons within a session, and simultaneous recordings from over 1000 neurons using multiple probes”
#neuroscience

You were interested in capturing retinal axons in mouse superior colliculus in vivo (doi.org/10.1038/s41467-022-32775-2)? You will be excited by thalamocortical axons in mouse cortex! Check out our latest story on mapping thalamocortical monosynaptic connectivity in vivo (doi.org/10.1101/2022.12.28.522000) using #Neuropixels. By @JeremieSibille and Carolin Gehr, funded by the DFG.

#introduction toot!! I am a neuroscientist at Instituto Cajal in Madrid, Spain. My lab studies how the 🧠hippocampus generates activity patterns (theta, gamma and ripple oscillations) in service for memory function. We target cell-type specific microcircuits and basic neurophysiological mechs in health & disease (e.g., epilepsy). We use #ephys #neuropixels #miniscopes #uLEDs #optogenetics #computationalneuroscience #machinelearning and love developing new #openscience tools & #neurotechnologies