"I’m glad to see this paper - it’s a look from Pfizer about how they were able to scale up #nirmatrelvir (the antiviral component of the #Paxlovid combination) so quickly. The authors are surely correct when they say that this 17-month timeline is a record for the drug industry, and it’s very much worth seeing how this all happened."
#Antiviral #drugdevelopment #covid19

https://www.science.org/content/blog-post/paxlovid-drug-development-full-sprint

New research article in The Lancet Infectious Diseases>

Effectiveness of #nirmatrelvir–#ritonavir in preventing hospital admissions and deaths in people with #COVID19: a cohort study in a large US health-care system

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099%2823%2900118-4/fulltext

New research article in The Lancet Infectious Diseases>

Real-world use of #nirmatrelvir–#ritonavir in outpatients with #COVID19 during the era of omicron variants including BA.4 and BA.5 in Colorado, USA: a retrospective cohort study

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00011-7/fulltext