Proteomic studies have uncovered a huge number of post-translational modifications on chaperones (over 100!). We like to think of these #PTMs like keys on a piano. Stresses to cells like heat or DNA damage cause a unique combination of keys (PTMs) to be played making a song (unique #Hsp70 function). We are trying to match stresses to each PTM and work out the function of this "chaperone code" in normal and cancerous cells. For more, please see: https://www.sciencedirect.com/science/article/pii/S0021925817501076?via%3Dihub