#PedsID A review of #AcuteKidneyInjury in children with moderate to severe #COVID & MISC. “the inflammation and cardiac dysfunction are associated with AKI in MIS-C patients".
Long term kidney monitoring is needed #LongCovidkids

https://link.springer.com/article/10.1007/s00467-023-06125-3

https://pubmed.ncbi.nlm.nih.gov/37676500/

#IDMastodon #PedsID @thelancetinfdis Several studies confirm #ViralPersistence in stillborn, in neonates, & in children But #LongCovid is not exceptional, or unique
Viral persistence in children infected with #SarsCoV2 current evidence and future research strategies
https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(23)00115-5/fulltext

#IDMastodon #PedsID Details on the pathogenesis, clinical presentation, and treatment for #postCOVID conditions in children are beyond the scope of these Guidelines. @CDCgov provides additional information about the incidence, presentation, and management strategies for #LongCovidKid as well as adults. @nih

#IDMastodon #PedsID @jama_current A diagnosis of #COVID19 in children was associated with an increased incidence of T1D since 2020. The findings suggest that #SARSCoV2 infection contributed to the observed increase in diabetes incidence during the pandemic.
📌 https://jamanetwork.com/journals/jama/fullarticle/2805461?guestAccessKey=cb6e6e53-fcbb-4a6b-b738-01a09c0533a5&utm_source=twitter&utm_medium=social_jama&utm_term=10082776656&utm_campaign=article_alert&linkId=215750581

#IDmastodon #PedsID @Sbernsteinmd #Casreports #Neurocovid #LongCovidKids
Long-term neurodevelopmental sequelae are a potential concern in #neonates following in utero exposure to #COVID19 in the midtrimester , maternal #SARSCoV2 infection can infect the placenta & fetal or infant brain & trigger a cascade of inflammatory events
📌 https://publications.aap.org/pediatrics/article/doi/10.1542/peds.2022-058271/191033/Maternal-SARS-CoV-2-Placental-Changes-and-Brain?autologincheck=redirected

#IDMastodon #PedsID @panhammarstrom @casanova_lab There is growing evidence to suggest that severe disease in children infected with common viruses or #SARSCoV2 that are benign in other children can result from inborn errors of immunity or their phenocopies. #COVID19 can lead to acute #hypoxemic in children with inborn errors of type I ( IFN) immunity or #Autoantibodies against IFNs.
📌 https://onlinelibrary.wiley.com/doi/epdf/10.1111/joim.13628
📌 https://pubmed.ncbi.nlm.nih.gov/36906905/

#IDMastodon #LongCovidkids #PedsID #CaseReport Guillain Barré syndrome in the paediatric population. Consequence of active infection or #LongCovid ?
📌 https://www.sciencedirect.com/science/article/pii/S2444440523000018
📌 https://www.sciencedirect.com/journal/revista-colombiana-de-reumatologia-english-edition/vol/29/issue/4

RT @accpinfdprn@twitter.com

We love to see dose optimization in our littlest patients! 🤩👶📈💊 #PedsID https://twitter.com/accppediprn/status/1618272034701840384

🐦🔗: https://twitter.com/accpinfdprn/status/1618277405902376961

#PedMastodon #PedsID #covid19 is not destroying kids immune systems. Conspiracy theories abound on the internet. They are wrong… @andrew_croxford . Time to bust the bizarre myth which emerged online that #COVID19 causes immunodeficiency in kids.This spread in a similar manner to anti-vaccine propaganda, using highly technical language to confuse and obfuscate It ends here by @apsmunro
https://alasdairmunro.substack.com/p/covid-is-not-destroying-kids-immune?sd=pf

#IDMastodon #PedsID in currently the most up-to-date seroprevalence study following multiple omicron waves in 🇬🇧 , estimate that nearly all children aged 1–17 years have been exposed to #SARSCoV2 irrespective of vaccination status. The findings have implications for future recommendations for childhood #COVID19 vaccination.
📌https://www.sciencedirect.com/science/article/pii/S0163445322007010?dgcid=coauthor

#IDMastodon #PedsID Overall, MIS-C can be caused by autosomal recessive defects of the OAS-RNase L pathway, which unleash the activation of mononuclear phagocytes by #SARSCoV2-triggered dsRNA, thereby possibly facilitating the expansion of Vbeta21.3 T cells. @aaas via @casanova_lab share by @yoncabulutmd
https://www.science.org/doi/10.1126/science.abd4570

First hint that there might be genetic defects in children with #MIS-C: "We report autosomal recessive deficiencies of OAS1, OAS2, or RNASEL in five unrelated children with MIS-C. "

Cool work from Jean-Laurent Cassanova and many team members:

https://www.science.org/doi/10.1126/science.abo3627

#IDMastodon #PedsIDMastodon #PedsID #SARSCov2

RT @MontefiorePeds
Are you a #MedStudent or #PedsResident interested in #Pediatric #InfectiousDiseases? Come visit us, rent-free, for a 4 wk rotation at the Children's Hospital at Montefiore (#CHAM). Work w/our award-winning faculty & dedicated clinician-educators. #PedsID https://www.cham.org/for-health-professionals/residency-and-fellowship-at-the-children-s-hospital-at-montefiore/visiting-pediatric-elective

RT @NCHforFellows
If you're looking for an exciting peds ID career in a stimulating educational & research environment and want to work with a wonderful #OneTeam starting July 2023, reach out re: an open #PedsID fellowship position @nationwidekids. Contact william.barson@nationwidechildrens.org 🦋

The future of infectious diseases? If you think that adult ID has a problem filling training positions in the 🇺🇸 (25.6% unfilled in the recent #FellowMatch): check peds ID - the majority of positions are unfilled!
#PedsID #MatchDay #IDMastodon #PedsIDMastodon #tootiatrician

RT @bassirih@twitter.com

We @CHOP_ID
are *absolutely thrilled* to be welcoming four rising stars into our ID community starting July 2023!

🐦 🔗 : https://twitter.com/bassirih/status/1598282220464386050?s=20&t=p3OoSSAPG9bw69ArSLXOeg

#PedsID #MatchDay #FellowMatch #IDMastodon #PedsID Mastodon #MedMastodon

RT @yoncabulutmd@twitter.com

25 million children missed their first dose of #Measles in 2021.#PedsICU #pedsID
#Measlesoutbreak #ohio 👇 https://twitter.com/aetiology/status/1597619684693925888

🐦🔗: https://twitter.com/yoncabulutmd/status/1597836855000838145

🙌 Excited to remeet & #introduce myself to the #Med-Mastodon 🐘 #IDSoMe Community:

🔬🦠🍄 Pediatric Infectious Diseases, passionate about clinical outcomes, infections & advancing care & access for #PICH 👶 Pediatric ImmunoCompromised Hosts, including #TransplantID #OncID & #OI in 1°ID or kids on #ImmunomodulatorTx. Associate Professor & Medical Director of #PediatricTICH ID @UTSouthwestern & @UTSWPedsGroup in #DallasTX, by way of #Montreal #Baltimore & #QueensNY. #PedsID #TxID #DEI #MedToots

#IDMastodon #Neurology #PedsID The incidence of new seizures or epilepsy diagnoses in 6 months following #COVID19 .Highlighting the risk of epilepsy and seizures even in those with less severe infection & #LongCovid .Children appear at particular risk of seizures ,epilepsy after #COVID19 providing another motivation to prevent #SarsCoV2 infection in pediatric populations.
📌https://n.neurology.org/content/neurology/early/2022/11/16/WNL.0000000000201595.full.pdf
📌https://n.neurology.org/content/early/2022/11/16/WNL.0000000000201595