@griggo_grig from presenting Phynteny at APG Awards Fest. 🧬🦠🔬🌟 You can predict the functions of unknown phage genes using an LSTM model trained with phage synteny.
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Check out Phynteny at https://github.com/susiegriggo/Phynteny
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#phages #bacteriophages #synteny #APGAwardsFest2023
#Phages #bacteriophages #synteny #apgawardsfest2023
Scientists discover how parasites of #viruses drive #superbug #evolution.
#phages #gene_transfer #lateral_transduction
https://phys.org/news/2023-08-scientists-parasites-viruses-superbug-evolution.html
#viruses #superbug #evolution #Phages #gene_transfer #lateral_transduction
According to the new #metagenome paper, #viruses / #phages of non-aquatic environments only outnumber cells by about two-fold (major capsid protein and universal SCGs used as markers). So the new estimation of virus/phage count might be far closer to cells. Interesting. #microbiology
#microbiology #metagenome #viruses #Phages
'#Bioprospecting' technique uncovers #viruses that can kill deadly superbugs.
#phages #antimicrobial #epitopes #porin
https://phys.org/news/2023-05-bioprospecting-technique-uncovers-viruses-deadly.html
#bioprospecting #viruses #Phages #antimicrobial #epitopes #porin
Hijacking strategy mapped for hundreds of #viruses.
#infection #protein #motif #phages
https://phys.org/news/2023-05-hijacking-strategy-hundreds-viruses.html
#viruses #infection #protein #motif #Phages
The anti-#CRISPR gene family AcrIF7 is mainly mobilized by temperate #phages, and is highly conserved due to slow co-evolution with its target; @wfigueroac3 @cazares_adr &co also identify residues involved in stability & mutational tolerance #PLOSBiology https://plos.io/40CqAS9
The anti-#CRISPR gene family AcrIF7 is mainly mobilized by temperate #phages, and is highly conserved due to slow co-evolution with its target; @wfigueroac3 @cazares_adr &co also identify residues involved in stability & mutational tolerance #PLOSBiology https://plos.io/40CqAS9
Unexplored diversity and ecological functions of transposable phages
RT @viji112
The preprint of Phables is up on biorxiv! Phables can resolve high-quality bacteriophage genomes in metagenomic data using assembly graphs.
@BeardyMcFace @BhavyaPapudeshi @susiegriggo_ @PDecewicz @GB13Faithless @linsalrob @LauraInglis13 @Marine_Rycrobe
#phages #Bioinformatics https://twitter.com/biorxiv_bioinfo/status/1643490370443935745
The preprint of Phables is up on biorxiv! Phables can resolve high-quality bacteriophage genomes in metagenomic data using assembly graphs.
Preprint: https://www.biorxiv.org/content/10.1101/2023.04.04.535632v1
GitHub: https://github.com/Vini2/phables
@BeardyMcJohnFace @npbhavya @griggo_grig @GB13Faithless @AbbeyHutton @linsalrob
#bacteriophages #phages #metagenomics #bioinformatics #software
#bacteriophages #Phages #metagenomics #bioinformatics #software
More's the Same-Multiple Hosts Do Not Select for Broader Host Range #Phages -
The unregulated potential of #phages - The Lancet Microbe
https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(23)00043-5/fulltext
Bacteria can shed a layer when #phages turn up the heat | Nature Microbiology
Identification and characterization of thousands of bacteriophage satellites across bacteria
https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad123/7068371?rss=1
#Phages #viruses #microbiology
.@vivek_mutalik@fediscience.or is studying RNA #phages with just four genes. In a new paper in @Nature Bio Chem, Mutalik & collaborators bring us closer to understanding how these tiny predators kill their hosts – and how we might one day use them to fight antibiotic resistance: http://ow.ly/Eyci50MZxYm
Illustration by Mutalik!
Super thrilled to share our new publication led by @ben_a_adler “Multicopy suppressor screens reveal convergent evolution of single-gene lysis proteins” on single strand RNA Fiersviridae #phages
https://www.nature.com/articles/s41589-023-01269-7.
Here is the link to our paper https://rdcu.be/c50Kp
PhageTailFinder: A tool for #phage tail module detection and annotation
#phages
https://www.frontiersin.org/articles/10.3389/fgene.2023.947466/full?utm_source=researcher_app