Associative overdominance has once again become a catch-all term that conflates pseudo-overdominance, apparent overdominance, and diversity-enhancing linked selection, due to the careless use of the term by big names in population genetics. This is unfortunate. #PopGen

Sweeps of previous variants were not synchronous between countries, but very close in time. A slight increase in the rate of migration, which seems likely given that everything has come back to free globalization, a lower selection coefficient, and this could give rise to a synchronous sweep on a global scale. #ba286 #PopGen

In Western Europe, we have several closely related grasshoppers belonging to the subgenus Glyptobothrus. The mitochondrial DNA phylogeny of four species (e.g., most
widespread: Chorthippus biggutulus, C. brunneus and C. mollis) is largely unresolved, with several species sharing surprisingly close mtDNA genomes and 100% similar COI barcodes (e.g. Hawlitschek et al.2017). I'm investigating the causes of this phylogenetic irresolution

#PopGen #EvolutionaryBiology #Evolution #Insects

1/n

"Are mutations random?" is a review of my book by
@Grey_Monroe

He focuses on scrutinizing randomness claims

Other args of interest:

(1) specialized mut systems (e.g., shuffling antigen genes in pathogens) are real (Ch. 5)

2) pop-gen theory today provides for a dispositional influence of variation— via introduction biases— unknown in the 20th century (Ch. 8)

(3) and empirical work shows the predicted dispositional influence of mut bias (Ch. 9)

https://academic.oup.com/evolut/article/doi/10.1093/evolut/qpad152/7252632

#popgen #mutation

A new preprint by Hilde Schneeman and John Welch using FGM to explore what we can infer from introgression line data. Quite a lot of overdominance in the reanalysed datasets, but it may well be transient (background dependent) and thus fixable. Again, an important read for anyone interested in hybridization. #PopGen #Hybridization

Transient overdominance, coadaptation, and the fixability of heterosis
https://www.biorxiv.org/content/10.1101/2023.08.23.554444v1

A new strain of Penicillium roqueforti discovered in Termignon cheese, a cheese I can't wait to taste, and lots of interesting results from this new paper by Tatiana Giraud's team, published in #EvolutionaryApplications
https://onlinelibrary.wiley.com/doi/10.1111/eva.13578
going together with a short video summary explaining domestication of cheese fungi
https://youtu.be/iN0A6dudWqI
#PopGen #PopulationGenomics #Biodiversity #Domestication

If you're at #icpp2023, come see my talk on #coevolution in a wild pathosytem in the #popgen session in 'Grand Salon Prestige' (please boost!)

#PopGen #EvolMol #ThalerConference #MustWatch #AlternativeSplicing #SplicingErrors #DriftBarrier Amazing talk by @duret_lbbe here on the SEEM youtube channel 👇

https://ecoevo.social/@couplingdmi/110860290160070455

Another day of working on Harpy and the first task is "user-proofing" the CLI. I know it's a little extra, but I can't stress how much compassion Harpy is developed with. I *want* to catch your errors early and I *want* you to know exactly where they are and how to fix them before rerunning.

#bioinformatics #dev #popgen #genomics

John Welch and Guillaume Martin in the same (my) office today 🤯 talking about Fisher's Geometric Model of course 😀 #PopGen

PhD proposal in Population genomics of hybridogenetic harvester ants.

https://emploi.cnrs.fr/Offres/Doctorant/UMR5554-JONROM-008/Default.aspx?lang=EN

Part of #ERC RoyalMess project.

Isem Montpellier

@jobsecoevo
#job #PopGen #evolution

sweepstakes drift or draft ?
Two interesting reads about #PopGen in in highly
fecund populations

https://elifesciences.org/articles/80781

https://onlinelibrary.wiley.com/share/QWBP2BMVUZV9PHQGDZD2?target=10.1111/mec.16903

Waited for the ink to dry to make sure it was real, but I'm beside myself w/ excitement to announce that I received the NSF PRF to do a #postdoc with Nina Therkildsen at Cornell. It's gonna be a wild ride of fish, rivers, #popgen, software dev, and Oxford commas.

Not bad for a kid born in Belarus, trained exclusively in the US public school system, and one more Oxford comma.

Our latest paper on polyploid population genetics is now out at Genetics! Led by Paul Blischak with Ryan Gutenkunst and Mathews Sajan we develop models in dadi to infer the demographic history of polyploid species. Check it out here: https://academic.oup.com/genetics/advance-article-abstract/doi/10.1093/genetics/iyad107/7190362?redirectedFrom=fulltext

#polyploidy #genetics #PopGen

Although there are some really good papers sometimes published in Nature Ecology and Evolution, I am nonetheless convinced that this journal has mainly been highly detrimental to our field #PopGen #BoycottGlamJournals #ProfessionalEditorsRuinScience

"**geneHapR: an R package for gene haplotypic statistics and visualization"**
https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-023-05318-9
#haplotype #popgen #PopulationGenetics #statistics #visualization #dataviz

A brief news piece on Sane, et al (2023) explains mut bias reversals and their potential importance in evo

The theory is developed in Tuffaha, et al (https://biorxiv.org/content/10.1101/2022.09.27.509708v2)

Bias reversals are not strongly favored if adaptation has gone on too long (so that the fast and slow steps in the DFE are all depleted) or too little

So, if they are common in nature, this seems to contradict much work in #popgen assuming a system close to the optimum

https://news.ncbs.res.in/research-explained/shifting-balance

@JoannaMasel

A #MustRead #preprint by @jeff_groh and @gcbias on the use of wavelet-based decompositions to study genome-wide selection against introgressed alleles 🤩 @darwin #Evolution #PopGen
https://www.biorxiv.org/content/10.1101/2023.05.25.542345v2

New paper thread! This one has been a long time coming, and I'm excited about it:
https://arxiv.org/abs/2305.14488
"Looking forwards and backwards", with Alison Etheridge, Tom Kurtz, Ian Letter, and Terence Tsui Ho Lung.
#PopGen #SpatialEcology

The Shifting Gene Frequencies paradigm, which has shaped evo thinking for generations, says

* evo is SGF
* evo happens in pops
* causes of evo are forces that shift freqs
* to study causes is to study #popgen
* all of evo (macroevo) follows from SGF

To understand ongoing debates about alternative causes and research programs, the SGFP is like the hidden part of the iceberg

It is one of the ways that the historic Synthesis reaches out to us from beyond the grave

1/?

https://youtu.be/g6CLDydPBjw