Long overdue #introduction. UK based systems biologist here. Experienced in modelling biological systems for #QSP drug discovery projects as well as data analysis and visualisation. Interested in all things #rstats and research software engineering. Currently looking for remote working research opportunities.

Physiologically-based PK (#PBPK) models, for example, find the middle ground between PK and #QSP, having a more mechanistic bent by taking into account anatomical, physiological, physical, and chemical descriptions of the phenomena involved in complex absorption, distribution, metabolic and elimination (#ADME) processes, while remaining fundamentally driven by observed data.

#QuantitativeSystemsPharmacology (#QSP) is also considered to be a part of the PMx ecosystem, but applies a more theoretical and less data-driven approach to building models. QSP models are often much more complex than PK/PD models, with less of a populations focus.