The bad:

"Nevertheless, these mechanisms yield viral selection. APOBEC expression in cancers leads to DNA damage and tumor cell death, yet allows for immune escape variants."

The verdict:

"Indeed, APOBECs are fickle friends."

#mutation
#cancer
#Apobec
#viruses
#virology
#RNAediting

Referenced link: https://phys.org/news/2023-06-octopuses-rna-rapidly-temperature-protein.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-06-octopuses-rna-rapidly-temperature-protein.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1666822442042658818#m

Study: #Octopuses use #RNAediting to rapidly respond to temperature changes by altering protein function @mblscience @CellCellPress https://linkinghub.elsevier.com/retrieve/pii/S0092867423005238 https://phys.org/news/2023-06-octopuses-rna-rapidly-temperature-protein.html

Referenced link: https://medicalxpress.com/news/2022-08-genetic-variants-dampen-a-to-i-rna.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2022-08-genetic-variants-dampen-a-to-i-rna.html

Originally posted by Phys.org / @physorg_com@twitter.com: https://twitter.com/medical_xpress/status/1560328190568140800#m

RT by @physorg_com: Genetic variants that dampen A-to-I #RNAediting associated with increased risk of autoimmune disorders @nature https://www.nature.com/articles/s41586-022-05052-x https://medicalxpress.com/news/2022-08-genetic-variants-dampen-a-to-i-rna.html

Referenced link: https://phys.org/news/2022-08-loss-rna-ca13-channel-spatial.html
Discuss on https://discu.eu/q/https://phys.org/news/2022-08-loss-rna-ca13-channel-spatial.html

Originally posted by Phys.org / @physorg_com@twitter.com: https://twitter.com/physorg_com/status/1558094722849292290#m

Loss of #RNAediting in the Caᵥ1.3 channel to enhance spatial memory comes at a price @NUSingapore @PNASNews @neurocellpress https://pnas.org/doi/full/10.1073/pnas.2203883119 https://phys.org/news/2022-08-loss-rna-ca13-channel-spatial.html