Stephen Matheson🌵🌲 · @sfmatheson
710 followers · 679 posts · Server fediscience.orgJulia Salzman from Stanford
http://salzmanlab.stanford.edu/
now explaining
SPLASH: Statistically Primary aLignment Agnostic Sequence Homing
We want to rapidly survey large #genomic areas, for regulatory sites, #splicing, etc. How do we look at sequencing data today? Through a lens of alignment with reference genomes. This can fail (e.g. cancer cells with shattered genomes, #V(D)J #recombination in immune cells)
Her metaphor: we need ground penetrating radar for #genomics
1/2
#cssinglecells23 #genomics #Recombination #v #splicing #genomic
CellBioNews · @cellbionews
78 followers · 1643 posts · Server scientificnetwork.deUnraveling the molecular basis of #Dmc1 filament assembly in #homologous #recombination.
https://phys.org/news/2023-07-unraveling-molecular-basis-dmc1-filament.html
#dmc1 #homologous #Recombination
Giuseppe Michieli · @GMIK69
74 followers · 1619 posts · Server mstdn.science'' It is possible for continuous #recombination to occur within #carbapenem-resistant #Enterobacteriaceae (#CRE) during infection. In contrast to exogenously-acquired resistance, greater attention should be placed on the endogenous factors that contribute to the development of CRE within healthcare settings.''
#Recombination #carbapenem #enterobacteriaceae #cre
JIPB · @JIPB
40 followers · 177 posts · Server mstdn.science
In an unexpected twist, Zhang et al. reveal that in #Maize, FIGL1 coordinates with dosage-sensitive #BRCA2 in modulating #meiotic #recombination, unlike their antagonistic relationship in #Arabidopsis.
https://doi.org/10.1111/jipb.13541
@wileyplantsci
#PlantSci #evolution #DNArepair #JIPB #plantscience
#Maize #BRCA2 #meiotic #Recombination #arabidopsis #plantsci #evolution #DNARepair #JIPB #plantscience
The EMBO Journal · @embojournal
455 followers · 214 posts · Server sciencemastodon.com
Local enhancers of the #PAIR4 regulatory module promote distal V-H gene #recombination at the #Igh locus and contribute to #Bcell receptor repertoire diversification
Louisa Hil et al Busslinger lab @IMPvienna
#pair4 #Recombination #igh #Bcell
The EMBO Journal · @embojournal
426 followers · 140 posts · Server sciencemastodon.com
A #protelysis cascade fine-tunes homologous #recombination repair in plants:
Arp Schnittger and coworkers show #KNOTEN1, stabilized by #UBP12/13, triggering K63-linked #ubiquitination and #autophagic degradation of #BLM complex subunit #RMI1 upon #DNAdamage
#protelysis #Recombination #knoten1 #ubp12 #ubiquitination #autophagic #BLM #rmi1 #dnadamage
Giuseppe Michieli · @GMIK69
54 followers · 968 posts · Server mstdn.sciencePotential #recombination between #SARS-CoV-2 and #MERS-CoV: calls for the development of Pan-CoV #vaccines, https://www.nature.com/articles/s41392-023-01396-6
#Recombination #sars #mers #vaccines
Daniel Fischer · @cosmos4u
1233 followers · 1738 posts · Server scicomm.xyzFirst detection of radio recombination lines of ions heavier than helium: https://www.aanda.org/articles/aa/full_html/2023/03/aa45904-23/aa45904-23.html -> Astronomers detect radio #recombination lines of carbon/oxygen ions for first time: https://www.eurekalert.org/news-releases/981756
Francois Sabot · @francois_sabot
316 followers · 802 posts · Server genomic.social
RT @PCIgenomics
New recommendation by @PeerCommunityIn #genomics, on performance and limitations of #linkage-disequilibrium-based methods for inferring the genomic landscape of #recombination by @Marie_Raynaud_, Pierre-Alexandre Gagnaire, @GaltierNicolas https://doi.org/10.1101/2022.03.30.486352
#genomics #linkage #Recombination
EMBO Reports · @emboreports
179 followers · 30 posts · Server sciencemastodon.com
The February issue is online:
https://embopress.org/toc/14693178/2023/24/2…
The cover features work by Quinghua Shi and co-workers showing that the #meiosis arresting #protein M1AP interacts with the ZZS complex and promotes #male meiotic #recombination.
-> https://www.embopress.org/doi/abs/10.15252/embr.202255778
#meiosis #protein #male #Recombination
Vivek Mutalik · @vivek_mutalik
655 followers · 782 posts · Server fediscience.orgIdentification of #integrons and gene cassette-associated #recombination sites in #bacteriophage genomes - PubMed
#bacteriophage #Recombination #integrons
Groms · @groms
140 followers · 2403 posts · Server mastodon.world
Kurianlab · @kurianlab
68 followers · 199 posts · Server sciencemastodon.comRT @todd_macfarlan
I am looking for a staff scientist to join my group at the NIH in Bethesda, Maryland. Competitive salary and benefits, good funding, and terrific colleagues! https://www.training.nih.gov/postdoc_jobs_nih/view/_31/10347/SSPMDB_1192023 #transposons #evolution #meiosis #recombination #retroviruses #development
#transposons #evolution #meiosis #Recombination #retroviruses #development
Rakoonin · @Rakoonin
4 followers · 715 posts · Server mastodon.online
RT @HollyBlomberg@twitter.com
What happens when you couple an ongoing pandemic (SARS-CoV-2) with a massive international event in a country where MERS-CoV-2 is endemic? #fafo #FIFAWorldCup2022 #recombination https://jessicawildfire.substack.com/p/get-ready-for-mers-cov-2
🐦🔗: https://twitter.com/HollyBlomberg/status/1603779641705369606
#Recombination #FIFAWorldCup2022 #FAFO
Vivek Mutalik · @vivek_mutalik
468 followers · 353 posts · Server fediscience.orgRecBCD enzyme and Chi #recombination #hotspots as determinants of self vs. non-self: Myths and mechanisms - #phage
#phage #Hotspots #Recombination
Philipp Markolin ☑️ · @protagonist_future
316 followers · 107 posts · Server mstdn.science
There is an important pre-print (https://www.biorxiv.org/content/10.1101/2022.11.23.517609v1) from Jiang Wang et al., about how common #viral #recombination is in bats; which has direct implications on the #originsofcovid as well as future #pandemic #prevention.
Gonna talk to one of the senior authors on the #preprint about this work; if you want me to ask any questions; you can post them as reply or DM here.
#viral #Recombination #originsofcovid #pandemic #prevention #preprint
PLOS Biology · @PLOSBiology
2986 followers · 176 posts · Server fediscience.org
DNA life preservers. #Caulobacter produces #prophage-like gene transfer agent that mediates survival in DNA damaging conditions by providing genomic DNA from donor cells for #recombination-based repair in recipients @Tung_BK_Le @michael_laub8 #PLOSBiology https://plos.io/3E0EyVR
#plosbiology #Recombination #prophage #caulobacter
GenomeBiolEvol · @GenomeBiolEvol
471 followers · 23 posts · Server ecoevo.social
The Linkage-Disequilibrium and Recombinational Landscape in Daphnia pulex https://buff.ly/3tJzD5C #science #evolution #biology #daphnia #recombination
#science #Evolution #biology #daphnia #Recombination
Nonia Pariente · @npariente
1001 followers · 286 posts · Server fediscience.org
RT @PLOSBiology
A combined population #genomic, #phylogenomic & pan-genomic approach reveals high levels of #recombination & metabolic diversity in the opportunistic fungal #pathogen #Aspergillus fumigatus @LotusLofgren @hyphaltip @cramer_lab #PLOSBiology https://plos.io/3tEuID5
#plosbiology #Aspergillus #pathogen #Recombination #phylogenomic #genomic
PLOS Biology · @PLOSBiology
1999 followers · 111 posts · Server fediscience.org
A combined population #genomic, #phylogenomic & pan-genomic approach reveals high levels of #recombination & metabolic diversity in the opportunistic fungal #pathogen #Aspergillus fumigatus @LotusLofgren @hyphaltip @cramer_lab #PLOSBiology https://plos.io/3tEuID5
#plosbiology #Aspergillus #pathogen #Recombination #phylogenomic #genomic