Using X-ray crystallography at the Advanced Light Source (ALS), research scientist Banumathi Sankaran at the Berkeley Center for Structural Biology (BCSB) has helped confirm the successful design of proteins that toggle between two different shapes in response to biological triggers.
Berkeley Lab #ProteinDesign #MachineLearning #StructuralBiology #Science #RoseTTAFold #ProteinMPNN #AlphaFold2
#proteindesign #MachineLearning #structuralbiology #science #RoseTTAFold #proteinmpnn #AlphaFold2
#question to #strucluralbiologists
Do you still use structural predictor threading based like #phyre2 since #AlphaFold2 #RoseTTAFold #meta
Please boost
#meta #RoseTTAFold #AlphaFold2 #phyre2 #strucluralbiologists #question
Has the #RoseTTAFold team done what #AlphaFold haven't managed to do, and accurately predict the effect of point mutations on protein structures? #xp
https://www.biorxiv.org/content/10.1101/2022.11.04.515218v1?rss=1
#xp #AlphaFold #RoseTTAFold #preprint #structuralbiology