LBNL BioSci · @LBNLBioSci
103 followers · 160 posts · Server sciencemastodon.com

Using X-ray crystallography at the Advanced Light Source (ALS), research scientist Banumathi Sankaran at the Berkeley Center for Structural Biology (BCSB) has helped confirm the successful design of proteins that toggle between two different shapes in response to biological triggers.

Read more: biosciences.lbl.gov/2023/08/29

Berkeley Lab

#proteindesign #MachineLearning #structuralbiology #science #RoseTTAFold #proteinmpnn #AlphaFold2

Last updated 1 year ago

François Ferron 🇪🇺 · @F2erron
61 followers · 61 posts · Server fediscience.org

to
Do you still use structural predictor threading based like since
Please boost

#meta #RoseTTAFold #AlphaFold2 #phyre2 #strucluralbiologists #question

Last updated 2 years ago

Dave Briggs :protein: · @xtaldave
692 followers · 913 posts · Server xtaldave.net

:

Has the team done what haven't managed to do, and accurately predict the effect of point mutations on protein structures?

biorxiv.org/content/10.1101/20

#xp #AlphaFold #RoseTTAFold #preprint #structuralbiology

Last updated 2 years ago