Nach 75 Jahren gelang es den verstorbenen #SomertonMan zu identifizieren. Die Leiche des Mannes wurde 1948 in Adelaine gefunden, Hinweise auf seine Identität gab es nicht. In den späten 2000ern begann der Forscher Derek Abbott sich mit seinem Team dem Fall zu widmen. Ein 5 cm langes Haar konnte 2022 nach vielen ergebnislosen Tests das Rätsel seiner #Identität lösen. In seiner #DNA waren 2 Millionen #SNPs zu finden, wodurch Angehörige ausfindig gemacht werden konnten.
#SNPs #dna #identitat #somertonman
My first #GTseq (Genotyping in Thousands by sequencing) protocol optimization. This is a #PCR based protocol that amplifies hundreds of target loci. The goal is to include in a single PCR reaction as much primer pairs as possible while minimising primer interactions and maximising target loci amplification. Each locus contains known #SNPs. The optimised GTseq panel will be used for population #GeneticMonitoring of the #endangered 𝘏𝘺𝘣𝘰𝘨𝘯𝘢𝘵𝘩𝘶𝘴 𝘢𝘮𝘢𝘳𝘶𝘴. More species coming. #ConservationGenomics
#gtseq #pcr #SNPs #geneticmonitoring #endangered #ConservationGenomics
RT @RoliRoberts
How do you select the “best” #SNPs for species ID, population ID, individual ID, sex, relatedness, etc? Nice talk from @_ellie_cat at #ConsGenPop22 - software tool on its way...
How could #DNAmethylation contribute to #mutation and #speciation in #whitefish species complexes? We explore this and more in our new #PrePrint!
Considerable #genetic and #epigenetic divergence between benthic-limnetic species
Enrichment of SNPs at CpG sites - methylation-induced #mutagenesis?
Also enriched overlaps between high #FST #SNPs and #DMLs - possible #GeneticAssimilation?
With amazing collaboration from @clairemerot @eric_normandeau and others
Read more: https://www.biorxiv.org/content/10.1101/2022.11.18.517126v1
#DNAmethylation #Mutation #Speciation #whitefish #preprint #genetic #epigenetic #mutagenesis #fst #SNPs #dmls #geneticassimilation
What an insightful talk from #MichaelFay at the Royal Institution. The annual Haldane Lecture hosted by the #GeneticsSociety.
We saw all the journey they've been through to try to answer conservation needs since the 1990s of the lady's slipper orchid. From #AFLPs to #GBS and #SNPs! How genetic techniques have evolved and are applied to the same organism is just so interesting!
#michaelfay #geneticssociety #aflps #gbs #SNPs
Genome scan spots common variant differences between autism and ADHD
https://www.spectrumnews.org/news/genome-scan-spots-common-variant-differences-between-autism-and-adhd/
#commonvariants #rarevariants #epigenetics #depression #diagnosis #autism #News #ADHD #SNPs
#commonvariants #rarevariants #epigenetics #depression #diagnosis #autism #news #ADHD #SNPs
New resource maps gene expression, regulation in neuron subtypes
https://www.spectrumnews.org/news/toolbox/new-resource-maps-gene-expression-regulation-in-neuron-subtypes/
#excitatorysignaling #inhibitorysignaling #bipolardisorder #geneexpression #schizophrenia #chromatin #glutamate #stemcells #Toolbox #autism #ADHD #GABA #SNPs
#excitatorysignaling #inhibitorysignaling #bipolardisorder #geneexpression #schizophrenia #chromatin #glutamate #stemcells #Toolbox #autism #ADHD #GABA #SNPs
Information loss may weaken autism genetic scores
https://www.spectrumnews.org/news/information-loss-may-weaken-autism-genetic-scores/
#autism #News #GWAS #SNPs
New resource tracks genetic variations in Han Chinese populations
https://www.spectrumnews.org/news/toolbox/new-resource-tracks-genetic-variations-in-han-chinese-populations/
#whole-genomesequencing #commonvariants #sequencing #Toolbox #autism #SNPs
#whole #commonvariants #sequencing #Toolbox #autism #SNPs
X chromosome exerts extra influence on brain development
https://www.spectrumnews.org/news/x-chromosome-exerts-extra-influence-on-brain-development/
#commonvariants #geneexpression #brainimaging #theoryofmind #sequencing #brainsize #autism #cortex #News #GWAS #SNPs #MRI #sex
#commonvariants #geneexpression #brainimaging #Theoryofmind #sequencing #brainsize #autism #Cortex #news #GWAS #SNPs #mri #sex
Patchwork mutations present a new frontier for autism research
https://www.spectrumnews.org/news/patchwork-mutations-present-a-new-frontier-for-autism-research/
#SimonsSimplexCollection #copynumbervariation #denovomutations #genetictesting #mosaicism #autism #News #SNPs
#SimonsSimplexCollection #copynumbervariation #denovomutations #genetictesting #mosaicism #autism #news #SNPs
Disrupted cell skeletons may explain brain wiring changes in autism-linked condition
https://www.spectrumnews.org/news/disrupted-cell-skeletons-may-explain-brain-wiring-changes-autism-linked-condition/
#inhibitorysignaling #tuberoussclerosis #News #SNPs #TSC2
#inhibitorysignaling #tuberoussclerosis #news #SNPs #TSC2