In flies:

"Using a transcriptomic analysis of over 37,000 nuclei, we identified twelve distinct clusters of cells corresponding to temperature-sensing arista neurons, humidity-sensing sacculus neurons, and support cells relating to these neurons."
#Preprint #SensoryNeuroscience #neuroscience

https://www.biorxiv.org/content/10.1101/2023.06.26.546511v1

"Transient receptor potential vanilloid 1 (TRPV1), a receptor for capsaicin and noxious heat, has been one of the most compelling targets for analgesics. However, systemic inhibition of TRPV1 is an impractical approach as a pain killer, since systemic antagonism induces hyperthermia. Two articles in this issue of the JCI report phenotypes from separate, rare missense mutations of human TRPV1."

#neuroscience #SensoryNeuroscience #trpv1

https://www.jci.org/articles/view/167338